Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6672 | Dimaprit dihydrochloride |
| Selective H2 agonist with central effects upon systemic administration. Also inhibits nNOS (IC50 = 49 μM). | |
| BCC6674 | BD 1008 dihydrobromide |
| Potent and selective σ-ligand (Ki against [3H]-(+)-3-PPP = 0.34 nM). | |
| BCC6683 | HEAT hydrochloride |
| Very selective α1-adrenoceptor antagonist, precursor of the 3-[125I]-derivative. | |
| BCC6686 | H-7 dihydrochloride |
| Protein kinase inhibitor. IC50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μM respectively. | |
| BCC6688 | Ifenprodil hemitartrate |
| NMDA receptor antagonist, acting at the polyamine site. Also an α-adrenergic vasodilator. σ2 ligand displaying about 3-fold selectivity over σ1 sites. | |
| BCC6692 | MMPX |
| Specific inhibitor of calmodulin-sensitive cyclic GMP phosphodiesterase (IC50 = 5.2 μM). | |
| BCC6694 | FG 7142 |
| Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β-adrenoceptors in mouse cerebral cortex. | |
| BCC6699 | PCA 4248 |
| A specific PAF antagonist, more potent than the ginkolide BN-52021. Inhibits rabbit platelet aggregation with an IC50 value of 1.05 μM and has no significant activity on Ca2+ channels. Active in vivo, antagonizing PAF-induced systemic hypotension and protein-plasma extravasation in rats. | |
