Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6784 | N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide |
| σ-1 selective ligand which binds with high affinity to human malignant melanoma cells A 2058. | |
| BCC6785 | SNC 80 |
| A highly selective and potent non-peptide δ-opioid agonist, 2000-fold selective over μ-opioid receptors. | |
| BCC6789 | Carboxy-PTIO, potassium salt |
| A stable, water-soluble free radical that reacts stoichiometrically with NO. Almost twice as strong an inhibitor as N(ω)-nitroarginine or N-methylarginine. | |
| BCC6792 | ICI 199,441 hydrochloride |
| Highly potent κ agonist, 146-fold more active than U-50488 in vitro. | |
| BCC6794 | NCS-382 |
| γ-Hydroxybutyric acid antagonist, anticonvulsant. | |
| BCC6796 | (±)-Anatoxin A fumarate |
| A potent nicotinic agonist (Ki values are 1.25 and 1840 nM for α4β2 and α7 nicotinic receptors respectively). Stimulates [3H]-dopamine release from rat striatal synaptosomes (EC50 = 136 nM). | |
| BCC6797 | Efaroxan hydrochloride |
| Potent, highly selective α2 adrenoceptor antagonist and imidazoline I1 receptor ligand (pKi values are 7.87, 7.42, 5.74, 7.28 and < 5 for α 2A, α2B, α2C, I1, and I2 receptors respectively). Promotes insulin secretion, at a site distinct from I1 or I2 (the putative I3 receptor) in vitro and in vivo. | |
| BCC6798 | Idazoxan hydrochloride |
| α2-adrenoceptor antagonist, and I2 ligand, selective over I1 sites (pKi values are 5.90, 7.22, 8.01, 7.43, and 7.7 for I1, I2, α2A, α2B, and α2C receptors respectively). | |
