Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6625 | A-7 hydrochloride |
| Potent calmodulin antagonist (inhibits calmodulin-activated PDE activity with an IC50 of 3 μM). | |
| BCC6626 | SKF 97541 |
| Very potent GABAB agonist, at least ten times more active than baclofen. Also GABAA-ρ antagonist. | |
| BCC6630 | Ambenonium dichloride |
| Extremely potent, selective and rapidly reversible inhibitor of acetylcholinesterase (AChE) (IC50 values are 0.000698 and 8.20 μM at AChE and BChE respectively). | |
| BCC6633 | (S)-(-)-Atenolol |
| The active enantiomer of (RS)-atenolol, a cardioselective β-adrenergic blocker. | |
| BCC6638 | Ro 20-1724 |
| Widely used inhibitor of cyclic nucleotide phosphodiesterase, selective for PDE4 (IC50 = 2.0 μM). Also available as part of the Phosphodiesterase Inhibitor. | |
| BCC6644 | ML 9 hydrochloride |
| Selective MLCK inhibitor (Ki values are 4, 32 and 54 μM for MLCK, PKA and PKC respectively). Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca2+ entry (SOCE). | |
| BCC6645 | MY-5445 |
| Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM). | |
| BCC6647 | Cimaterol |
| β-Adrenergic agonist. | |
