Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6799 | DIPPA hydrochloride |
| An irreversible and selective antagonist at the κ receptor, with persistent effect in vivo. | |
| BCC6803 | THIP hydrochloride |
| Systemically active GABAA receptor agonist and GABAA-ρ receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats. | |
| BCC6804 | (±)-threo-3-Methylglutamic acid |
| A potent blocker of glutamate transport; selective for EAAT2 and EAAT4 (IC50 values are 90, 109, 1600 and 1080 μM for EAAT2, EAAT4, EAAT1 and EAAT3 respectively). | |
| BCC6807 | ICI 89406 |
| β-adrenergic antagonist and low efficacy partial agonist; does not affect resting cardiac parameters. | |
| BCC6809 | (S)-(-)-Propranolol hydrochloride |
| More active enantiomer of the β-adrenoceptor antagonist propranolol. (R)-(+)-Propranolol hydrochloride also available. | |
| BCC6810 | (R)-(+)-Propranolol hydrochloride |
| Less active enantiomer of the β-adrenoceptor antagonist propranolol. (S)-(-)-Propranolol hydrochloride also available. | |
| BCC6812 | DTG |
| Displays high and roughly equal affinity for both σ1 and σ2 receptors. | |
| BCC6816 | Chicago Sky Blue 6B |
| Potent inhibitor of L-glutamate uptake into synaptic vesicles. Allosterically inhibits macrophage migration inhibitory factor (MIF) (IC50 = 0.81 μM); inhibits MIF proinflammatory activity. | |
