Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6741 | 2-MPMDQ |
| Potent and selective α1-adrenoceptor antagonist; hypotensive. | |
| BCC6750 | (±)-Epibatidine |
| High affinity nicotinic agonist (Ki values are 0.02 and 233 nM for α4β2 and α7 nicotinic receptors respectively). Analgesic. | |
| BCC6751 | BRL 52537 hydrochloride |
| The most κ/μ-selective and among the most potent κ ligands known (25 times more potent than morphine in vivo). | |
| BCC6766 | Pyrrolidinedithiocarbamate ammonium |
| This inhibitor of nuclear factor κB (NF-κB) prevents the increase in NO-synthase mRNA by interleukin-1, without affecting the formation of NO-synthase mRNA produced by cAMP. | |
| BCC6777 | 4-IBP |
| Combines high affinity for σ1 and moderate affinity for σ2 sites. Centrally active following systemic administration in vivo. | |
| BCC6780 | SM-21 maleate |
| Potent and selective σ2 antagonist with central effects following systemic administration. Causes increased release of acetylcholine at central muscarinic synapses. Potent analgesic (efficacy comparable to morphine) and nootropic agent. | |
| BCC6782 | N-Benzylnaltrindole hydrochloride |
| Potent δ2-selective opioid receptor antagonist with a long duration of action in vivo. | |
| BCC6783 | Castanospermine |
| Potent inhibitor of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication. | |
