Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6700 | (S)-(+)-α-Methylhistamine dihydrobromide |
| Less active enantiomer of H3 agonist R-(-)-α-methylhistamine; 120-fold less potent than R-(-) at H3. | |
| BCC6703 | Tyrphostin B44, (-) enantiomer |
| Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), more active than the (+) enantiomer. Selective over ErbB2. | |
| BCC6704 | Tyrphostin B44, (+) enantiomer |
| Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.86 μM). Slightly less active than the (-) enantiomer. | |
| BCC6705 | 3-MPPI |
| Very potent ligand for α1 sites (Ki for displacement of prazosin = 0.2 nM). Displays different binding properties for each α1 subtype (pKi values are 8.74, 9.44 and 9.57 for α1B, α1D and α1A adrenoceptors respectively). Also binds to 5-HT1A sites (Ki = 50 nM). | |
| BCC6710 | Naloxonazine dihydrochloride |
| Potent opioid antagonist, selective for μ1 receptors. | |
| BCC6711 | NPPB |
| Inhibits calcium-sensitive chloride currents (10 μM). Putative GPR35 agonist. | |
| BCC6717 | 17-ODYA |
| Potent suicide inhibitor of LTB4 ω-hydroxylase. | |
| BCC6720 | AG 556 |
| Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 1.1 μM). Selective over ErbB2 (IC50 > 500 μM). | |
