Home >> Research Area >>Natural Products>>Flavonoids>> 2,3-Dehydrokievitone

2,3-Dehydrokievitone

CAS# 74161-25-4

2,3-Dehydrokievitone

Catalog No. BCN4294----Order now to get a substantial discount!

Product Name & Size Price Stock
2,3-Dehydrokievitone: 5mg $190 In Stock
2,3-Dehydrokievitone: 10mg Please Inquire In Stock
2,3-Dehydrokievitone: 20mg Please Inquire Please Inquire
2,3-Dehydrokievitone: 50mg Please Inquire Please Inquire
2,3-Dehydrokievitone: 100mg Please Inquire Please Inquire
2,3-Dehydrokievitone: 200mg Please Inquire Please Inquire
2,3-Dehydrokievitone: 500mg Please Inquire Please Inquire
2,3-Dehydrokievitone: 1000mg Please Inquire Please Inquire

Quality Control of 2,3-Dehydrokievitone

Number of papers citing our products

Chemical structure

2,3-Dehydrokievitone

3D structure

Chemical Properties of 2,3-Dehydrokievitone

Cas No. 74161-25-4 SDF Download SDF
PubChem ID 5746354 Appearance Yellow powder
Formula C20H18O6 M.Wt 354.4
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-enyl)chromen-4-one
SMILES CC(=CCC1=C(C=C(C2=C1OC=C(C2=O)C3=C(C=C(C=C3)O)O)O)O)C
Standard InChIKey RWDSADRZXTYPMY-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2,3-Dehydrokievitone

The herbs of Erythrina arborescens

Biological Activity of 2,3-Dehydrokievitone

Description2,3- Dehydrokievitone exhibits strong cytotoxic activity and induces apoptosis efficiently in cancer cells.
In vitro

Antioxidative and Antitumor Effects of Isoflavones Isolated from the Leaves of Maackia fauriei [Reference: WebLink]

Rec. Nat. Prod., 2016, 10(4):441-51.

The flowers of Maackia fauriei have traditionally been used to treat hypertension, apoplexy, hemostasis, vaginal bleeding, and dystocia; moreover, the bark of this plant has been used as a natural dye. In the present study, activity-guided isolation of the leaves of M. fauriei yielded five isoflavones [genistein (1), pratensein (2), genistin (3), 2'-hydroxygenistein-7-O-β-D-glucopyranoside (4), and 2,3-Dehydrokievitone (5)]; three pterocarpans [medicarpin (6), maackiain (7), and 4-hydroxy maackiain (8)]; and one flavonol [isoquercitrin (9)].
METHODS AND RESULTS:
To evaluate the anti-oxidative effects of these compounds, their 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assays and nitrotetrazolium blue chloride (NBT) superoxide scavenging assays were measured. And the anti-tumor activity against human cancer cell lines in genital system, LNCaP, PC-3,HeLa and OVCAR-3 cells were evaluated by MTT method. Furthermore, the apoptosis of the PC-3 and HeLa cells were determined by by annexin V-FITC and PI their fluorescence was analyzed by flow cytometry. The flavonol (9, isoquercitrin) and pterocarpan (8, 4-hydroxymaackiain) showed strong anti-oxidative activities. Besides, the isoflavones (1-5) did not showed anti-oxidative activity and the isoflavones (1-5) and pterocarpans (6-8) generally showed the potent cytotoxic activity against all of four human genital cancer cells. Especially, 2,3-Dehydrokievitone (5) which had a prenyl group at C-8 position of the A-ring exhibited strong cytotoxic activity and induced apoptosis efficiently in cancer cells.

Protocol of 2,3-Dehydrokievitone

Structure Identification
Phytochemistry. 2000 Nov;55(5):457-9.

Two isoflavanones from the stem bark of Erythrina sacleuxii.[Pubmed: 11140607]


METHODS AND RESULTS:
From the stem bark of Erythrina sacleuxii two new isoflavanones, (R)-5,7-dihydroxy-2',4',5'-trimethoxyisoflavanone (trivial name, (R)-2,3-dihydro-7-demethylrobustigenin) and (R)-5-hydroxy-2',4',5'-trimethoxy-2",2"-dimethylpyrano[5",6":6,7]isoflavanone (trivial name, (R)-saclenone) were isolated. In addition the known compounds shinpterocarpin, 2,3-Dehydrokievitone, abyssinone V, abyssinone V-4'-methyl ether, erythrinasinate and 4'-O-methylsigmoidin B were isolated.
CONCLUSIONS:
The structures were determined on the basis of spectroscopic evidence.

2,3-Dehydrokievitone Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

2,3-Dehydrokievitone Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 2,3-Dehydrokievitone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8217 mL 14.1084 mL 28.2167 mL 56.4334 mL 70.5418 mL
5 mM 0.5643 mL 2.8217 mL 5.6433 mL 11.2867 mL 14.1084 mL
10 mM 0.2822 mL 1.4108 mL 2.8217 mL 5.6433 mL 7.0542 mL
50 mM 0.0564 mL 0.2822 mL 0.5643 mL 1.1287 mL 1.4108 mL
100 mM 0.0282 mL 0.1411 mL 0.2822 mL 0.5643 mL 0.7054 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 2,3-Dehydrokievitone

Two isoflavanones from the stem bark of Erythrina sacleuxii.[Pubmed:11140607]

Phytochemistry. 2000 Nov;55(5):457-9.

From the stem bark of Erythrina sacleuxii two new isoflavanones, (R)-5,7-dihydroxy-2',4',5'-trimethoxyisoflavanone (trivial name, (R)-2,3-dihydro-7-demethylrobustigenin) and (R)-5-hydroxy-2',4',5'-trimethoxy-2",2"-dimethylpyrano[5",6":6,7]isoflavanone (trivial name, (R)-saclenone) were isolated. In addition the known compounds shinpterocarpin, 2,3-Dehydrokievitone, abyssinone V, abyssinone V-4'-methyl ether, erythrinasinate and 4'-O-methylsigmoidin B were isolated. The structures were determined on the basis of spectroscopic evidence.

Keywords:

2,3-Dehydrokievitone,74161-25-4,Natural Products, buy 2,3-Dehydrokievitone , 2,3-Dehydrokievitone supplier , purchase 2,3-Dehydrokievitone , 2,3-Dehydrokievitone cost , 2,3-Dehydrokievitone manufacturer , order 2,3-Dehydrokievitone , high purity 2,3-Dehydrokievitone

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: