Home >> Research Area >>Natural Products>>Sesquiterpenoids>> 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

CAS# 1175543-03-9

2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

Catalog No. BCN7741----Order now to get a substantial discount!

Product Name & Size Price Stock
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 5mg $1150 In Stock
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 10mg Please Inquire In Stock
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 20mg Please Inquire Please Inquire
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 50mg Please Inquire Please Inquire
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 100mg Please Inquire Please Inquire
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 200mg Please Inquire Please Inquire
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 500mg Please Inquire Please Inquire
2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene: 1000mg Please Inquire Please Inquire

Quality Control of 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

Number of papers citing our products

Chemical structure

2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

3D structure

Chemical Properties of 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

Cas No. 1175543-03-9 SDF Download SDF
PubChem ID 44480214 Appearance Powder
Formula C15H24O4 M.Wt 268.34
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4R,4aS,6S,8aS)-4,6-dihydroxy-4-(hydroxymethyl)-3,4a,8,8-tetramethyl-5,6,7,8a-tetrahydronaphthalen-1-one
SMILES CC1=CC(=O)C2C(CC(CC2(C1(CO)O)C)O)(C)C
Standard InChIKey MMMVWBXLRFTTSV-HQRZJTNHSA-N
Standard InChI InChI=1S/C15H24O4/c1-9-5-11(18)12-13(2,3)6-10(17)7-14(12,4)15(9,19)8-16/h5,10,12,16-17,19H,6-8H2,1-4H3/t10-,12-,14-,15+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

The culture medium of the marine-derived fungus Aspergillus insuetus (OY-207).

Biological Activity of 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

Description2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene is a natural product from the culture medium of the marine-derived fungus Aspergillus insuetus (OY-207).

Protocol of 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

Structure Identification
Bioorg Med Chem. 2011 Nov 15;19(22):6587-93.

Novel terpenoids of the fungus Aspergillus insuetus isolated from the Mediterranean sponge Psammocinia sp. collected along the coast of Israel.[Pubmed: 21676619 ]


METHODS AND RESULTS:
Three novel meroterpenoids, insuetolides A-C (1-3) and four drimane sesquiterpenes, the new (E)-6-(4'-hydroxy-2'-butenoyl)-strobilactone A (4) and the known 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene (5), strobilactone A (6) and (E,E)-6-(6',7'-dihydroxy-2',4'-octadienoyl)-strobilactone A (7), were isolated from the EtOAc extract of the culture medium of the marine-derived fungus Aspergillus insuetus (OY-207), which was isolated from the Mediterranean sponge Psammocinia sp. The structures of the compounds were determined by spectroscopic methods. Insuetolides A-C reveal a new carbon skeleton derived from the cyclization of farnesyl and 3, 5-dimethylorsellinic acid.
CONCLUSIONS:
Compounds 1, 6, and 7 exhibited anti-fungal activity towards Neurospora crassa with MIC values of 140, 242, and 162 μM, respectively; and compounds 3, 4, and 7 exhibited mild cytotoxicity towards MOLT-4 human leukemia cells.

2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7266 mL 18.6331 mL 37.2662 mL 74.5323 mL 93.1654 mL
5 mM 0.7453 mL 3.7266 mL 7.4532 mL 14.9065 mL 18.6331 mL
10 mM 0.3727 mL 1.8633 mL 3.7266 mL 7.4532 mL 9.3165 mL
50 mM 0.0745 mL 0.3727 mL 0.7453 mL 1.4906 mL 1.8633 mL
100 mM 0.0373 mL 0.1863 mL 0.3727 mL 0.7453 mL 0.9317 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

Novel terpenoids of the fungus Aspergillus insuetus isolated from the Mediterranean sponge Psammocinia sp. collected along the coast of Israel.[Pubmed:21676619]

Bioorg Med Chem. 2011 Nov 15;19(22):6587-93.

Three novel meroterpenoids, insuetolides A-C (1-3) and four drimane sesquiterpenes, the new (E)-6-(4'-hydroxy-2'-butenoyl)-strobilactone A (4) and the known 2alpha, 9alpha, 11-trihydroxy-6-oxodrim-7-ene (5), strobilactone A (6) and (E,E)-6-(6',7'-dihydroxy-2',4'-octadienoyl)-strobilactone A (7), were isolated from the EtOAc extract of the culture medium of the marine-derived fungus Aspergillus insuetus (OY-207), which was isolated from the Mediterranean sponge Psammocinia sp. The structures of the compounds were determined by spectroscopic methods. Insuetolides A-C reveal a new carbon skeleton derived from the cyclization of farnesyl and 3, 5-dimethylorsellinic acid. Compounds 1, 6, and 7 exhibited anti-fungal activity towards Neurospora crassa with MIC values of 140, 242, and 162 muM, respectively; and compounds 3, 4, and 7 exhibited mild cytotoxicity towards MOLT-4 human leukemia cells.

Keywords:

2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene,1175543-03-9,Natural Products, buy 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene , 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene supplier , purchase 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene , 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene cost , 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene manufacturer , order 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene , high purity 2alpha,9alpha,11-Trihydroxy-6-oxodrim-7-ene

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: