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Albaspidin AP

CAS# 59092-91-0

Albaspidin AP

Catalog No. BCN2398----Order now to get a substantial discount!

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Quality Control of Albaspidin AP

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Chemical structure

Albaspidin AP

3D structure

Chemical Properties of Albaspidin AP

Cas No. 59092-91-0 SDF Download SDF
PubChem ID 25096734 Appearance Powder
Formula C22H26O8 M.Wt 418.44
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-acetyl-4-[(2,6-dihydroxy-3,3-dimethyl-4-oxo-5-propanoylcyclohexa-1,5-dien-1-yl)methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
SMILES CCC(=O)C1=C(C(=C(C(C1=O)(C)C)O)CC2=C(C(C(=O)C(=C2O)C(=O)C)(C)C)O)O
Standard InChIKey KINDGCLGBSBXOD-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Albaspidin AP

The rhizomes of Dryopteris crassirhizoma Nakai

Biological Activity of Albaspidin AP

Description1. Albaspidin-AP, -PP, -PB inhibit Fatty acid synthase (FAS) with IC50 values ranging from 23.1+/-1.4 to 71.7+/-3.9 microM, they could be considered to be a promising class of FAS inhibitors, and FAS is emerging as a potential therapeutic target to treat cancer and obesity.
TargetsFatty Acid Synthase

Albaspidin AP Dilution Calculator

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Albaspidin AP Molarity Calculator

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Preparing Stock Solutions of Albaspidin AP

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3898 mL 11.9491 mL 23.8983 mL 47.7966 mL 59.7457 mL
5 mM 0.478 mL 2.3898 mL 4.7797 mL 9.5593 mL 11.9491 mL
10 mM 0.239 mL 1.1949 mL 2.3898 mL 4.7797 mL 5.9746 mL
50 mM 0.0478 mL 0.239 mL 0.478 mL 0.9559 mL 1.1949 mL
100 mM 0.0239 mL 0.1195 mL 0.239 mL 0.478 mL 0.5975 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Albaspidin AP

Studies on active constituents in rhizome of Dryopteris crassirhizoma

《Journal of Tianjin Medical University》 2007-02

Nine acylphloroglucinol derivatives were obtained and were identified ,the first three compounds of them:albaspidin AA(Ⅰ),Albaspidin AP(Ⅱ) and albasspidin PP(Ⅲ). Conclusion: Albaspidin AP,Ⅲ are first obtained as crystals from natural plants and are first found from Dryopteris Crassirhizoma. 1H-NMR and 13C-NMR data of Albaspidin AP and compound Ⅲ, and 13C-NMR data of compoundⅠ are first reported.

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