(+)-RhododendrolCAS# 59092-94-3 |
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| Cas No. | 59092-94-3 | SDF | Download SDF |
| PubChem ID | 919204 | Appearance | Powder |
| Formula | C10H14O2 | M.Wt | 166.22 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4-[(3S)-3-hydroxybutyl]phenol | ||
| SMILES | CC(CCC1=CC=C(C=C1)O)O | ||
| Standard InChIKey | SFUCGABQOMYVJW-QMMMGPOBSA-N | ||
| Standard InChI | InChI=1S/C10H14O2/c1-8(11)2-3-9-4-6-10(12)7-5-9/h4-8,11-12H,2-3H2,1H3/t8-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The plants of Acer nikoense Maxim.
| Description | 1. (+)-Rhododendrol shows anti-inflammatory effects, it can suppress the NO production by activated macrophages in vivo. |
| Targets | NO |
(+)-Rhododendrol Dilution Calculator
(+)-Rhododendrol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 6.0161 mL | 30.0806 mL | 60.1612 mL | 120.3225 mL | 150.4031 mL |
| 5 mM | 1.2032 mL | 6.0161 mL | 12.0322 mL | 24.0645 mL | 30.0806 mL |
| 10 mM | 0.6016 mL | 3.0081 mL | 6.0161 mL | 12.0322 mL | 15.0403 mL |
| 50 mM | 0.1203 mL | 0.6016 mL | 1.2032 mL | 2.4064 mL | 3.0081 mL |
| 100 mM | 0.0602 mL | 0.3008 mL | 0.6016 mL | 1.2032 mL | 1.504 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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(+)-rhododendrol and epi-rhododendrin suppress the NO production by activated macrophages in vivo.[Pubmed:9810263]
Planta Med. 1998 Oct;64(7):598-602.
In this study, we investigated the effect of (+)-Rhododendrol (1) and epi-rhododendrin (2) isolated from Acer nikoense Maxim. (Aceraceae) on nitric oxide (NO) production in mouse peritoneal macrophages elicited by bacillus Calmette-Guerin and in vitro stimulated by lipopolysaccharide. The NO production was not affected by an oral administration of methanol extract at a dose of 100 mg/kg/day. However, the AcOEt soluble fraction significantly reduced the NO production. (+)-Rhododendrol (1) isolated as an active substance from the AcOEt fraction suppressed the NO production. epi-Rhododendrin (2), the glucoside of (+)-Rhododendrol (1) isolated from the n-BuOH fraction, also suppressed the NO production. As NO is one of the critical mediators in inflammation, these results suggest that (+)-Rhododendrol (1) and epi-rhododendrin (2) contribute in part to the anti-inflammatory effect of A. nikoense.
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