Tolazoline HClCAS# 59-97-2 |
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| Cas No. | 59-97-2 | SDF | Download SDF |
| PubChem ID | 6048 | Appearance | Powder |
| Formula | C10H13ClN2 | M.Wt | 196.68 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | H2O : ≥ 50 mg/mL (254.22 mM) DMSO : 33.33 mg/mL (169.46 mM; Need ultrasonic) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | 2-benzyl-4,5-dihydro-1H-imidazole;hydrochloride | ||
| SMILES | C1CN=C(N1)CC2=CC=CC=C2.Cl | ||
| Standard InChIKey | RHTNTTODYGNRSP-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C10H12N2.ClH/c1-2-4-9(5-3-1)8-10-11-6-7-12-10;/h1-5H,6-8H2,(H,11,12);1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Tolazoline HCl Dilution Calculator
Tolazoline HCl Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.0844 mL | 25.422 mL | 50.844 mL | 101.688 mL | 127.11 mL |
| 5 mM | 1.0169 mL | 5.0844 mL | 10.1688 mL | 20.3376 mL | 25.422 mL |
| 10 mM | 0.5084 mL | 2.5422 mL | 5.0844 mL | 10.1688 mL | 12.711 mL |
| 50 mM | 0.1017 mL | 0.5084 mL | 1.0169 mL | 2.0338 mL | 2.5422 mL |
| 100 mM | 0.0508 mL | 0.2542 mL | 0.5084 mL | 1.0169 mL | 1.2711 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.
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[Tolazoline-HCl in cardio-respiratory adaptation of newborns with respiratory distress syndrome (author's transl)].[Pubmed:7335091]
Monatsschr Kinderheilkd. 1981 Oct;129(10):571-4.
The pharmacological effects of Tolazoline were studied in newborns with different types of pulmonary diseases. The drug was given when the arterial pO2 remained below 6,65 kP in spite of PEEP, and when the right-to-left shunt was greater than 60%. Continuous monitoring of arterial blood pressure and pO2 were of particular importance. Permanent improvement was found in 50%. Transitional improvement in 30% of the cases and in the remaining 20% the drug had no observable effect.
Tolazoline (hydrochloride)(Imidaline (hydrochloride)) Hcl is a non-selective competitive α-adrenergic receptor antagonist.
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