Carasinol B

CAS# 777857-86-0

Carasinol B

Catalog No. BCN8226----Order now to get a substantial discount!

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Carasinol B: 5mg $380 In Stock
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Quality Control of Carasinol B

Number of papers citing our products

Chemical structure

Carasinol B

3D structure

Chemical Properties of Carasinol B

Cas No. 777857-86-0 SDF Download SDF
PubChem ID 11309056 Appearance Powder
Formula C56H44O13 M.Wt 925.0
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5-[(2S,3R,4S,5R)-4-[(2S,3S)-3-[(2R,3R)-3-(3,5-dihydroxyphenyl)-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-4-yl]-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-4-yl]-2,5-bis(4-hydroxyphenyl)oxolan-3-yl]benzene-1,3-diol
SMILES C1=CC(=CC=C1C2C(C(C(O2)C3=CC=C(C=C3)O)C4=CC(=CC5=C4C(C(O5)C6=CC=C(C=C6)O)C7=CC(=CC8=C7C(C(O8)C9=CC=C(C=C9)O)C1=CC(=CC(=C1)O)O)O)O)C1=CC(=CC(=C1)O)O)O
Standard InChIKey RAUCCLKIJHMTND-HFRYPGABSA-N
Standard InChI InChI=1S/C56H44O13/c57-33-9-1-27(2-10-33)53-47(31-17-37(61)21-38(62)18-31)49-43(23-41(65)25-45(49)67-53)52-50-44(24-42(66)26-46(50)68-55(52)29-5-13-35(59)14-6-29)51-48(32-19-39(63)22-40(64)20-32)54(28-3-11-34(58)12-4-28)69-56(51)30-7-15-36(60)16-8-30/h1-26,47-48,51-66H/t47-,48+,51-,52+,53+,54-,55-,56+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Carasinol B

The herb of Carex humilis Leyss

Biological Activity of Carasinol B

DescriptionCarasinol B is a natural product from Carex humilis Leyss.

Protocol of Carasinol B

Structure Identification
Biol Pharm Bull. 2006 Apr;29(4):608-12.

Simultaneous determination of the contents of three stilbene oligomers in Caragana sinica collected in different seasons using an improved HPLC method.[Pubmed: 16595888]


METHODS AND RESULTS:
The objectives of this research were to determine simultaneously the contents of two stilbene tetramers, Carasinol B (1) and kobophenol A (2), and one stilbene trimer, (+)-alpha-viniferin (3), in the roots, tubers, and leaves of Caragana sinica in various seasons. A HPLC method has been developed for efficiently quantifying the three analytes in the plant. Using this method, different samples of Caragana sinica were evaluated.
CONCLUSIONS:
The results showed that the contents of 1, 2, and 3 in the roots were much higher than those in the tubers, and the contents of stilbene tetramers were maximal in winter while the contents of the stilbene trimer were maximal in summer. Compounds 1, 2, and 3 could not be detected in the flowers of Caragana sinica in our detection ranges.

Carasinol B Dilution Calculator

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Carasinol B Molarity Calculator

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Preparing Stock Solutions of Carasinol B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0811 mL 5.4054 mL 10.8108 mL 21.6216 mL 27.027 mL
5 mM 0.2162 mL 1.0811 mL 2.1622 mL 4.3243 mL 5.4054 mL
10 mM 0.1081 mL 0.5405 mL 1.0811 mL 2.1622 mL 2.7027 mL
50 mM 0.0216 mL 0.1081 mL 0.2162 mL 0.4324 mL 0.5405 mL
100 mM 0.0108 mL 0.0541 mL 0.1081 mL 0.2162 mL 0.2703 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Carasinol B

Quantitative determination of stilbene oligomers in Jin Que-gen collected from different regions by a HPLC method.[Pubmed:16755062]

Chem Pharm Bull (Tokyo). 2006 Jun;54(6):878-81.

The objectives of this research were to determine simultaneously the contents of two stilbene tetramers, Carasinol B (1) and kobophenol A (2), and one stilbene trimer, (+)-alpha-viniferin (3), in Jin Que-gen in different regions. A HPLC method has been developed for efficiently quantifying the three analytes in the plant. Using this method, different samples of Jin Que-gen were evaluated. The results showed that contents of the three analytes varied significantly among different samples, and the contents of the three analytes in commercial Jin Que-gen were markedly lower than those in the plants collected directly from growing regions. And for the three analytes, the longer the cultivation time, the higher the contents.

Simultaneous determination of the contents of three stilbene oligomers in Caragana sinica collected in different seasons using an improved HPLC method.[Pubmed:16595888]

Biol Pharm Bull. 2006 Apr;29(4):608-12.

The objectives of this research were to determine simultaneously the contents of two stilbene tetramers, Carasinol B (1) and kobophenol A (2), and one stilbene trimer, (+)-alpha-viniferin (3), in the roots, tubers, and leaves of Caragana sinica in various seasons. A HPLC method has been developed for efficiently quantifying the three analytes in the plant. Using this method, different samples of Caragana sinica were evaluated. The results showed that the contents of 1, 2, and 3 in the roots were much higher than those in the tubers, and the contents of stilbene tetramers were maximal in winter while the contents of the stilbene trimer were maximal in summer. Compounds 1, 2, and 3 could not be detected in the flowers of Caragana sinica in our detection ranges.

Acid-catalyzed epimerization of kobophenol A to carasinol B.[Pubmed:18463595]

Molecules. 2008 Apr 19;13(4):938-42.

The conversion from kobophenol A into Carasinol B, two main chemical constituents of Caragana sinica, was confirmed by in vitro acid-catalyzed epimerization. The result provides important information about the biotransformation of kobophenol A in plants and its metabolism in rats.

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