Secologanin dimethyl acetalCAS# 77988-07-9 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 77988-07-9 | SDF | Download SDF |
| PubChem ID | 157140 | Appearance | Powder |
| Formula | C19H30O11 | M.Wt | 434.44 |
| Type of Compound | Iridoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | methyl (2S,3R,4S)-4-(2,2-dimethoxyethyl)-3-ethenyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylate | ||
| SMILES | COC(CC1C(C(OC=C1C(=O)OC)OC2C(C(C(C(O2)CO)O)O)O)C=C)OC | ||
| Standard InChIKey | HUVIXLWRQSMCLN-PXRCHJMLSA-N | ||
| Standard InChI | InChI=1S/C19H30O11/c1-5-9-10(6-13(25-2)26-3)11(17(24)27-4)8-28-18(9)30-19-16(23)15(22)14(21)12(7-20)29-19/h5,8-10,12-16,18-23H,1,6-7H2,2-4H3/t9-,10+,12-,14-,15+,16-,18+,19+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Secologanin dimethyl acetal induces significant neurite outgrowth. |
Secologanin dimethyl acetal Dilution Calculator
Secologanin dimethyl acetal Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3018 mL | 11.5091 mL | 23.0181 mL | 46.0363 mL | 57.5453 mL |
| 5 mM | 0.4604 mL | 2.3018 mL | 4.6036 mL | 9.2073 mL | 11.5091 mL |
| 10 mM | 0.2302 mL | 1.1509 mL | 2.3018 mL | 4.6036 mL | 5.7545 mL |
| 50 mM | 0.046 mL | 0.2302 mL | 0.4604 mL | 0.9207 mL | 1.1509 mL |
| 100 mM | 0.023 mL | 0.1151 mL | 0.2302 mL | 0.4604 mL | 0.5755 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Z-Glycinol
Catalog No.:BCC3095
CAS No.:77987-49-6
- Longikaurin E
Catalog No.:BCN4329
CAS No.:77949-42-9
- Dinaciclib (SCH727965)
Catalog No.:BCC3765
CAS No.:779353-01-4
- Doxazosin Mesylate
Catalog No.:BCC1257
CAS No.:77883-43-3
- Beta-Lipotropin (1-10), porcine
Catalog No.:BCC1009
CAS No.:77875-68-4
- Isopulegol
Catalog No.:BCN4974
CAS No.:7786-67-6
- Oglemilast
Catalog No.:BCC1817
CAS No.:778576-62-8
- (1R)-(+)-Alpha-Pinene
Catalog No.:BCC8275
CAS No.:7785-70-8
- Nelumol A
Catalog No.:BCN4749
CAS No.:77836-86-3
- GNF 5
Catalog No.:BCC3892
CAS No.:778277-15-9
- GNF 2
Catalog No.:BCC3891
CAS No.:778270-11-4
- Carasinol B
Catalog No.:BCN8226
CAS No.:777857-86-0
- Mulberrofuran C
Catalog No.:BCN4032
CAS No.:77996-04-4
- Isophorone
Catalog No.:BCN8329
CAS No.:78-59-1
- Linalool
Catalog No.:BCN6339
CAS No.:78-70-6
- Zeylasterone
Catalog No.:BCN8057
CAS No.:78012-25-6
- 1,3-Diacetylvilasinin
Catalog No.:BCN4580
CAS No.:78012-28-9
- MMPX
Catalog No.:BCC6692
CAS No.:78033-08-6
- Fmoc-Lys(Fmoc)-OH
Catalog No.:BCC3521
CAS No.:78081-87-5
- (R)-(+)-8-Hydroxy-DPAT hydrobromide
Catalog No.:BCC6929
CAS No.:78095-19-9
- 2-Acetylfluorene
Catalog No.:BCC8516
CAS No.:781-73-7
- Aztreonam
Catalog No.:BCC2557
CAS No.:78110-38-0
- Okadaic acid
Catalog No.:BCC2464
CAS No.:78111-17-8
- DAMGO
Catalog No.:BCC6958
CAS No.:78123-71-4
New physiological function of secoiridoids: neuritogenic activity in PC12h cells.[Pubmed:20652643]
J Nat Med. 2011 Jan;65(1):186-90.
Previously, we have reported that geniposide isolated from an extract of Gardenia fructus has neuritogenic activity in PC12h cells, a subclone of rat pheochromocytoma cells. Furthermore, we have indicated that several geniposide-related iridoid compounds also had similar potent neuritogenic activity. In this study, we have examined the effects of various secoiridoid compounds [K-1, sweroside; K-2, swertiamarin; K-3, gentiopicroside; K-4, 6'-O-beta-D: -glucopyranosylsweroside; K-5, 6'-O-beta-D: -glucopyranosylgentiopicroside; K-6, 6'-O-beta-D: -glucopyranosylswertiamarin; K-7, 5'-O-beta-D: -glucopyranosylamarogentin; K-8, 5'-O-beta-D: -glucopyranosylamaroswertin; H-1, n-butyl vogeloside; H-2, n-butyl epivogeloside; H-3, (7S)-secologanin butyl methyl acetal; H-4, (7R)-secologanin butyl methyl acetal; H-5, Secologanin dimethyl acetal] isolated from various medicinal herbs. The secoiridoids H-1, H-2, H-3, H-4, and H-5 induced significant neurite outgrowth. Among these H-series compounds, H-2 was the most potent neuritogenic compound. Among the K-series compounds, K-1, K-2, K-3, and K-8 showed the most potent activity. These results suggest that secoiridoids have neuritogenic activity in PC12h cells and that these secoiridoid compounds are promising starting compounds for the development of neurotrophic factor-like and iridoid compounds.
