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Ergosterol glucoside

CAS# 130155-33-8

Ergosterol glucoside

Catalog No. BCN7327----Order now to get a substantial discount!

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Ergosterol glucoside: 5mg $886 In Stock
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Quality Control of Ergosterol glucoside

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Chemical structure

Ergosterol glucoside

3D structure

Chemical Properties of Ergosterol glucoside

Cas No. 130155-33-8 SDF Download SDF
PubChem ID 44176397 Appearance Powder
Formula C34H54O6 M.Wt 558.8
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3R,4S,5S,6R)-2-[[(3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C
Standard InChIKey MKZPNGBJJJZJMI-GBLVNJONSA-N
Standard InChI InChI=1S/C34H54O6/c1-19(2)20(3)7-8-21(4)25-11-12-26-24-10-9-22-17-23(13-15-33(22,5)27(24)14-16-34(25,26)6)39-32-31(38)30(37)29(36)28(18-35)40-32/h7-10,19-21,23,25-32,35-38H,11-18H2,1-6H3/b8-7+/t20-,21+,23-,25+,26-,27-,28+,29+,30-,31+,32+,33-,34+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ergosterol glucoside

The roots of Rehmannia glutinosa

Biological Activity of Ergosterol glucoside

DescriptionErgosterol glucoside is a natural product from Rehmannia glutinosa.
In vivo

Sterol glucosyltransferases have different functional roles in Pichia pastoris and Yarrowia lipolytica.[Pubmed: 14585290]

Cell Biol Int. 2003;27(11):947-52.


METHODS AND RESULTS:
Mutants of the methanol-utilizing yeast Pichia pastoris and the alkane-utilizing yeast Yarrowia lipolytica defective in the orthologue of UGT51 (encoding sterol glucosyltransferase) were isolated and compared. These mutants do not contain the specific ergosterol derivate, Ergosterol glucoside. We observed that the P. pastoris UGT51 gene is required for pexophagy, the process by which peroxisomes containing methanol-metabolizing enzymes are selectively shipped to and degraded in the vacuole upon shifting methanol-grown cells of this yeast to glucose or ethanol. PpUGT51 is also required for other vacuole related processes. In contrast, the Y. lipolytica UGT51 gene is required for utilization of decane, but not for pexophagy.
CONCLUSIONS:
Thus, sterol glucosyltransferases play different functional roles in P. pastoris and Y. lipolytica.

Ergosterol glucoside Dilution Calculator

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Ergosterol glucoside Molarity Calculator

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Preparing Stock Solutions of Ergosterol glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7895 mL 8.9477 mL 17.8955 mL 35.791 mL 44.7387 mL
5 mM 0.3579 mL 1.7895 mL 3.5791 mL 7.1582 mL 8.9477 mL
10 mM 0.179 mL 0.8948 mL 1.7895 mL 3.5791 mL 4.4739 mL
50 mM 0.0358 mL 0.179 mL 0.3579 mL 0.7158 mL 0.8948 mL
100 mM 0.0179 mL 0.0895 mL 0.179 mL 0.3579 mL 0.4474 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ergosterol glucoside

Sterol glucosyltransferases have different functional roles in Pichia pastoris and Yarrowia lipolytica.[Pubmed:14585290]

Cell Biol Int. 2003;27(11):947-52.

Mutants of the methanol-utilizing yeast Pichia pastoris and the alkane-utilizing yeast Yarrowia lipolytica defective in the orthologue of UGT51 (encoding sterol glucosyltransferase) were isolated and compared. These mutants do not contain the specific ergosterol derivate, Ergosterol glucoside. We observed that the P. pastoris UGT51 gene is required for pexophagy, the process by which peroxisomes containing methanol-metabolizing enzymes are selectively shipped to and degraded in the vacuole upon shifting methanol-grown cells of this yeast to glucose or ethanol. PpUGT51 is also required for other vacuole related processes. In contrast, the Y. lipolytica UGT51 gene is required for utilization of decane, but not for pexophagy. Thus, sterol glucosyltransferases play different functional roles in P. pastoris and Y. lipolytica.

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