Ganoderone A

CAS# 873061-79-1

Ganoderone A

Catalog No. BCN2448----Order now to get a substantial discount!

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Quality Control of Ganoderone A

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Chemical structure

Ganoderone A

3D structure

Chemical Properties of Ganoderone A

Cas No. 873061-79-1 SDF Download SDF
PubChem ID 11705156 Appearance Powder
Formula C30H46O3 M.Wt 454.68
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (5R,10S,13R,14R,17R)-17-[(E,2R)-7-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,7-dione
SMILES CC(CCC=C(C)CO)C1CCC2(C1(CCC3=C2C(=O)CC4C3(CCC(=O)C4(C)C)C)C)C
Standard InChIKey SDAWCNCFVWQZDP-GOUGDUPLSA-N
Standard InChI InChI=1S/C30H46O3/c1-19(18-31)9-8-10-20(2)21-11-16-30(7)26-22(12-15-29(21,30)6)28(5)14-13-25(33)27(3,4)24(28)17-23(26)32/h9,20-21,24,31H,8,10-18H2,1-7H3/b19-9+/t20-,21-,24+,28-,29-,30+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ganoderone A

The fruit body of Ganoderma lucidum

Biological Activity of Ganoderone A

Description1. Ganoderone A exhibits potent inhibitory activity against herpes simplex virus. 2. Ganoderone A exhibits strong inhibitory activities against Vero cells (IC50 is 0.3 ug/mL). 3. Ganoderone A has inhibition against cancer cell lines K562, SW620, and HL60, the 50% inhibiting concentration( IC50) are 9. 61, 22. 38, 7. 14 mg/L, respectively.
TargetsHSV | Integrase

Ganoderone A Dilution Calculator

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Ganoderone A Molarity Calculator

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Preparing Stock Solutions of Ganoderone A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1993 mL 10.9967 mL 21.9935 mL 43.987 mL 54.9837 mL
5 mM 0.4399 mL 2.1993 mL 4.3987 mL 8.7974 mL 10.9967 mL
10 mM 0.2199 mL 1.0997 mL 2.1993 mL 4.3987 mL 5.4984 mL
50 mM 0.044 mL 0.2199 mL 0.4399 mL 0.8797 mL 1.0997 mL
100 mM 0.022 mL 0.11 mL 0.2199 mL 0.4399 mL 0.5498 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ganoderone A

Antiviral Terpenoid Constituents of Ganoderma pfeifferi.[Pubmed:16378363]

J Nat Prod. 2005 Dec;68(12):1728-31.

Four sterols and 10 triterpenes were isolated from the fruiting bodies of Ganoderma pfeifferi, including the three new triterpenes 3,7,11-trioxo-5alpha-lanosta-8,24-diene-26-al (lucialdehyde D, 1), 5alpha-lanosta-8,24-diene-26-hydroxy-3,7-dione (Ganoderone A, 2), and 5alpha-lanosta-8-ene-24,25-epoxy-26-hydroxy-3,7-dione (ganoderone C, 3). The structures of 1-3 were determined on the basis of spectroscopic evidence. Antibacterial, antifungal, and antiviral activity were studied for some of the isolated compounds. Ganoderone A (2), lucialdehyde B (4), and ergosta-7,22-dien-3beta-ol (7) were found to exhibit potent inhibitory activity against herpes simplex virus.

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