Kuguacin N

CAS# 1141453-73-7

Kuguacin N

Catalog No. BCN3056----Order now to get a substantial discount!

Product Name & Size Price Stock
Kuguacin N: 5mg Please Inquire In Stock
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Quality Control of Kuguacin N

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Chemical structure

Kuguacin N

3D structure

Chemical Properties of Kuguacin N

Cas No. 1141453-73-7 SDF Download SDF
PubChem ID 25243361 Appearance Powder
Formula C30H46O4 M.Wt 470.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3S,7S,8S,9R,10R,13R,14S,17R)-3,7-dihydroxy-4,4,13,14-tetramethyl-17-[(2R)-6-methyl-4-oxohept-5-en-2-yl]-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-9-carbaldehyde
SMILES CC(CC(=O)C=C(C)C)C1CCC2(C1(CCC3(C2C(C=C4C3CCC(C4(C)C)O)O)C=O)C)C
Standard InChIKey NHGYTKMVBMBCNA-IFMVJOGVSA-N
Standard InChI InChI=1S/C30H46O4/c1-18(2)14-20(32)15-19(3)21-10-11-29(7)26-24(33)16-23-22(8-9-25(34)27(23,4)5)30(26,17-31)13-12-28(21,29)6/h14,16-17,19,21-22,24-26,33-34H,8-13,15H2,1-7H3/t19-,21-,22-,24+,25+,26+,28-,29+,30-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Kuguacin N

The fruits of Momordica charantia

Biological Activity of Kuguacin N

DescriptionKuguacin N has antioxidant activity.

Protocol of Kuguacin N

Structure Identification
Scientia Agricultura Sinica, 2017.

Saponion Profiles and Antioxidant Activity,α-Glucosidase Inhibitory Activity of Momordica charantia of Different Varieties[Reference: WebLink]

The content and composition of saponion of 13 different M. charantia varieties as well as the antioxidant activity and inhibitory effect of α-glucosidase were studied.
METHODS AND RESULTS:
Perchloric acid-vanilin-glacial method was used to determine saponin content, while HPLC method was used to measure the contents of 7 saponin components. In addition, their antioxidant activity was evaluated by oxygen radical absorbance capacity (ORAC). The 4-nitrophenyl-2-β-D-glucopyranoside method was used to measure the a-glucosidase inhibitory activity and to analyze the relationship between the components and the corresponding activity. There is a significant difference in contents of saponin in 13 different varieties of M charantia.The content ranges of saponin were 0.52-1.20 g/100g DW, with an average value being 0.79 g/100g DW, and the coefficient of variability being 21.65%. The average contents of components were as follows: momorcharaside A 5.32 μg•g⁻¹ DW, momordicoside A 25.42 (μg•g⁻¹ DW, karaviloside XI 3.96 μg•g⁻¹ DW, momordicoside F2 66.95 μg•g⁻¹ DW, momordicoside K 183.70 μg•g⁻¹ DW, (23E)-3p,7p,25-trihydroxycucubita-5,23-dien-19-al 40.13 μg•g⁻¹ DW, and Kuguacin N 3.87 μg•g⁻¹ DW. ORAC values of the 13 M. charantia varieties varied from 2 747.76 to 15 584.07 μmol Trolox•g⁻¹, the average value being 8 879.48 mol Trolox•g⁻¹, the coefficient of variability being 34.91% and the IC50 value of alpha glucosidase varied from 1.55 to 4.96 mg•mL⁻¹.
CONCLUSIONS:
Significant differences in the components of saponin and the antioxidant activity and the inhibitory effect on α-glucosidase of different varieties of M. charantia were detected. Saponin is the main active basis of a-glucosidase activity in M. charantia, but not the main antioxidant substance. (23E)-3p,7p,25-trihydroxycucubita-5,23-dien-19-al is the major active compound.

Kuguacin N Dilution Calculator

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Kuguacin N Molarity Calculator

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Preparing Stock Solutions of Kuguacin N

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1245 mL 10.6225 mL 21.245 mL 42.4899 mL 53.1124 mL
5 mM 0.4249 mL 2.1245 mL 4.249 mL 8.498 mL 10.6225 mL
10 mM 0.2124 mL 1.0622 mL 2.1245 mL 4.249 mL 5.3112 mL
50 mM 0.0425 mL 0.2124 mL 0.4249 mL 0.8498 mL 1.0622 mL
100 mM 0.0212 mL 0.1062 mL 0.2124 mL 0.4249 mL 0.5311 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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