Magnoflorine chlorideCAS# 6681-18-1 |
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| Cas No. | 6681-18-1 | SDF | Download SDF |
| PubChem ID | 23149 | Appearance | Yellow-brown powder |
| Formula | C20H24NO4Cl | M.Wt | 377.87 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Synonyms | Corytuberine methochloride; Escholine chloride; Thalictrine chloride | ||
| Solubility | Soluble in ethanol and water | ||
| Chemical Name | (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol;chloride | ||
| SMILES | C[N+]1(CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)O)OC)C.[Cl-] | ||
| Standard InChIKey | STVJLBTYWBXDBP-ZOWNYOTGSA-N | ||
| Standard InChI | InChI=1S/C20H23NO4.ClH/c1-21(2)8-7-12-10-15(25-4)20(23)18-16(12)13(21)9-11-5-6-14(24-3)19(22)17(11)18;/h5-6,10,13H,7-9H2,1-4H3,(H-,22,23);1H/t13-;/m0./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
1 Actaea sp. 2 Anamirta sp. 3 Aquilegia sp. 4 Aristolochia sp. 5 Berberis sp. 6 Caltha sp. 7 Caulophyllum sp. 8 Chelidonium sp. 9 Corydalis sp. 10 Eschscholzia sp. 11 Helleborus sp. 12 Magnolia sp. 13 Mahonia sp. 14 Zanthoxylum sp.
| Description | Magnoflorine is usually used as an anxiolytic chemical with anti-oxidant, α-tyrosinase inhibitory and anti-inflammationary activities. |
| Targets | Immunology & Inflammation related |
| Structure Identification | Planta Medica 1998, 64(2):165-171Alkaloids from Thalictrum przewalskii.[Reference: WebLink]Nine new alkaloids przewaline, przewalskine, przewalskinine, przewalstine, przewalstinine, przewalstidine, przewalstidinine, przewalidine chloride, and 8-hydroxypseudocoptisine chloride were isolated from Thalictrum przewalskii Maxim., together with the known alkaloids berberinium chloride, Magnoflorine chloride, N-methylpalaudinium chloride, thalphenine chloride, and N-methylnantenium chloride. Their structures were determined by spectroscopy including EI-MS, FAB-MS, (1)H-NMR, (13)C-NMR, C,H-COSY, C,H-COLOC, HMQC and HMBC techniques. |
Magnoflorine chloride Dilution Calculator
Magnoflorine chloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6464 mL | 13.2321 mL | 26.4641 mL | 52.9283 mL | 66.1603 mL |
| 5 mM | 0.5293 mL | 2.6464 mL | 5.2928 mL | 10.5857 mL | 13.2321 mL |
| 10 mM | 0.2646 mL | 1.3232 mL | 2.6464 mL | 5.2928 mL | 6.616 mL |
| 50 mM | 0.0529 mL | 0.2646 mL | 0.5293 mL | 1.0586 mL | 1.3232 mL |
| 100 mM | 0.0265 mL | 0.1323 mL | 0.2646 mL | 0.5293 mL | 0.6616 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Alkaloids from Thalictrum przewalskii.[Pubmed:17253231]
Planta Med. 1998 Mar;64(2):165-71.
Nine new alkaloids przewaline, przewalskine, przewalskinine, przewalstine, przewalstinine, przewalstidine, przewalstidinine, przewalidine chloride, and 8-hydroxypseudocoptisine chloride were isolated from Thalictrum przewalskii Maxim., together with the known alkaloids berberinium chloride, Magnoflorine chloride, N-methylpalaudinium chloride, thalphenine chloride, and N-methylnantenium chloride. Their structures were determined by spectroscopy including EI-MS, FAB-MS, (1)H-NMR, (13)C-NMR, C,H-COSY, C,H-COLOC, HMQC and HMBC techniques.
6-O-beta-D-glucoside of aristolochic acid IIIa and other components from the roots of Aristolochia baetica.[Pubmed:17252385]
Planta Med. 1997 Dec;63(6):579.
From the root extract of the European Aristolochia baetica L. we isolated aristolochic acid IIIa-6-O-beta-D-glucoside (1) besides Magnoflorine chloride, the free aristolochic acids I and II, and five aristolactams. Saccharose and fructose were found as major constituents.
Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity.
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