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Syringaresinol-di-O-glucoside

CAS# 66791-77-3

Syringaresinol-di-O-glucoside

2D Structure

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3D structure

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Syringaresinol-di-O-glucoside

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Chemical Properties of Syringaresinol-di-O-glucoside

Cas No. 66791-77-3 SDF Download SDF
PubChem ID 442830 Appearance White powder
Formula C34H46O18 M.Wt 742.71
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in methanol and water
Chemical Name (2S,3R,4S,5S,6R)-2-[4-[(3R,3aS,6R,6aS)-6-[3,5-dimethoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES COC1=CC(=CC(=C1OC2C(C(C(C(O2)CO)O)O)O)OC)C3C4COC(C4CO3)C5=CC(=C(C(=C5)OC)OC6C(C(C(C(O6)CO)O)O)O)OC
Standard InChIKey FFDULTAFAQRACT-NYYYOYJKSA-N
Standard InChI InChI=1S/C34H46O18/c1-43-17-5-13(6-18(44-2)31(17)51-33-27(41)25(39)23(37)21(9-35)49-33)29-15-11-48-30(16(15)12-47-29)14-7-19(45-3)32(20(8-14)46-4)52-34-28(42)26(40)24(38)22(10-36)50-34/h5-8,15-16,21-30,33-42H,9-12H2,1-4H3/t15-,16-,21-,22-,23-,24-,25+,26+,27-,28-,29+,30+,33+,34+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Syringaresinol-di-O-glucoside

1 Ilex sp. 2 Phellodendron sp.

Biological Activity of Syringaresinol-di-O-glucoside

DescriptionSyringaresinol-di-O-glucoside protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the stress-induced enlargement of adrenal gland.
In vivo

Effect of Eleutherococcus senticosus and Its Components on Sex- and Learning-Behaviours and Tyrosine Hydroxylase Activities of Adrenal Gland and Hypothalamic Regions in Chronic Stressed Mice[Reference: WebLink]

The Japanese journal of pharmacognosy 39(3), 238-242, 1985-09-20

Eleutherococcus senticosus and its components, syringin and Syringaresinol-di-O-glucoside, were studied for their effect on sex behaviours and on acquired conditioned reactions in mice exposed to chronic "hanging stress."
METHODS AND RESULTS:
Rectal temperature was recorded during exposure to the stress, and adrenal gland weight, tyrosine hydroxylase activity in adrenal gland and hypothalamic regions, and corticosterone content in adrenal gland and serum were measured 24 hr after the final exposure to stress. A water extract from Eleutherococcus senticosus and syringin were shown to protect mice from the stress-induced decreases in sex behaviors and in rectal temperature. Syringaresinol-di-O-glucoside protected the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the stress-induced enlargement of adrenal gland.
CONCLUSIONS:
They have no effect however on the stress-induced increase in tyrosine hydroxylase activity in adrenal gland and hypothalamic regions, and on corticosterone contents in adrenal gland and serum.

Syringaresinol-di-O-glucoside Dilution Calculator

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Preparing Stock Solutions of Syringaresinol-di-O-glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3464 mL 6.7321 mL 13.4642 mL 26.9284 mL 33.6605 mL
5 mM 0.2693 mL 1.3464 mL 2.6928 mL 5.3857 mL 6.7321 mL
10 mM 0.1346 mL 0.6732 mL 1.3464 mL 2.6928 mL 3.3661 mL
50 mM 0.0269 mL 0.1346 mL 0.2693 mL 0.5386 mL 0.6732 mL
100 mM 0.0135 mL 0.0673 mL 0.1346 mL 0.2693 mL 0.3366 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Syringaresinol diglucoside is a natural compound from bamboo leaves.

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