Medicagenic acidCAS# 599-07-5 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 599-07-5 | SDF | Download SDF |
| PubChem ID | 65048 | Appearance | White powder |
| Formula | C30H46O6 | M.Wt | 502.68 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Synonyms | Castanogenin | ||
| Solubility | Soluble in methan | ||
| Chemical Name | (2S,3R,4S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-2,3-dihydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylic acid | ||
| SMILES | CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C(=O)O)O)O)C)C)C2C1)C)C(=O)O)C | ||
| Standard InChIKey | IDGXIXSKISLYAC-WNTKNEGGSA-N | ||
| Standard InChI | InChI=1S/C30H46O6/c1-25(2)11-13-30(24(35)36)14-12-27(4)17(18(30)15-25)7-8-20-26(3)16-19(31)22(32)29(6,23(33)34)21(26)9-10-28(20,27)5/h7,18-22,31-32H,8-16H2,1-6H3,(H,33,34)(H,35,36)/t18-,19-,20+,21+,22-,26+,27+,28+,29-,30-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Medicago sativa
| Description | 1. Medicagenic acid derivatives exhibit potent fungistatic effects against several plant pathogens and human dermatophytes. 2. Medicagenic acid, the factor responsible for hemolytic activity of lucerne saponins. |
| Targets | Antifection |
Medicagenic acid Dilution Calculator
Medicagenic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9893 mL | 9.9467 mL | 19.8934 mL | 39.7867 mL | 49.7334 mL |
| 5 mM | 0.3979 mL | 1.9893 mL | 3.9787 mL | 7.9573 mL | 9.9467 mL |
| 10 mM | 0.1989 mL | 0.9947 mL | 1.9893 mL | 3.9787 mL | 4.9733 mL |
| 50 mM | 0.0398 mL | 0.1989 mL | 0.3979 mL | 0.7957 mL | 0.9947 mL |
| 100 mM | 0.0199 mL | 0.0995 mL | 0.1989 mL | 0.3979 mL | 0.4973 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Mesopsin
Catalog No.:BCN8050
CAS No.:5989-16-2
- Loliolid
Catalog No.:BCN3655
CAS No.:5989-02-6
- 7-hydroxy-4-benzopyrone
Catalog No.:BCC9209
CAS No.:59887-89-7
- ent-7alpha,9-Dihydroxy-15-oxokaur-16-en-19,6bet-olide
Catalog No.:BCN7401
CAS No.:59885-89-1
- N-Formyl-Met-Leu-Phe
Catalog No.:BCC7205
CAS No.:59880-97-6
- L-Dihydroorotic acid
Catalog No.:BCC9007
CAS No.:5988-19-2
- Glabridin
Catalog No.:BCN1221
CAS No.:59870-68-7
- Oxybuprocaine HCl
Catalog No.:BCC4691
CAS No.:5987-82-6
- Cyclosporin A
Catalog No.:BCC4773
CAS No.:59865-13-3
- Patchouli alcohol
Catalog No.:BCN4966
CAS No.:5986-55-0
- Palustrol
Catalog No.:BCN4100
CAS No.:5986-49-2
- Synephrine HCl
Catalog No.:BCC4359
CAS No.:5985-28-4
New Products
- 3,3'-Sulfonyldianiline
Catalog No.:BCC8595
CAS No.:599-61-1
- Sulfasalazine
Catalog No.:BCC2545
CAS No.:599-79-1
- 3-Hydroxy-8,9-methylenedioxypterocarpene
Catalog No.:BCN1407
CAS No.:59901-98-3
- Vicenin -3
Catalog No.:BCN3014
CAS No.:59914-91-9
- HPI 1
Catalog No.:BCC3938
CAS No.:599150-20-6
- Vindesine sulfate
Catalog No.:BCC8266
CAS No.:59917-39-4
- Vicriviroc maleate
Catalog No.:BCC2038
CAS No.:599179-03-0
- 3',4'-dihydro-3'-hydroxy-Xanthyletin
Catalog No.:BCN3680
CAS No.:5993-18-0
- Malotilate
Catalog No.:BCC1196
CAS No.:59937-28-9
- Carlinoside
Catalog No.:BCN2853
CAS No.:59952-97-5
- Tagitinin F
Catalog No.:BCN4101
CAS No.:59979-57-6
- Tagitinin A
Catalog No.:BCN4102
CAS No.:59979-61-2
Saponins as antimycotic agents: glycosides of medicagenic acid.[Pubmed:8957322]
Adv Exp Med Biol. 1996;404:535-46.
The continuous search for new antimycotic drugs is a consequence of the broad use of immunosuppressive drugs and broad-spectrum antibiotics, high number of AIDS patients, and widespread dermatophyte infections. The concern with increased resistance due to widespread and prolonged antifungal treatment, particularly with azoles, is noteworthy. Our efforts were focused on Medicagenic acid derivatives isolated from alfalfa and on semisynthetic ones. In general, these materials exhibited potent fungistatic effects against several plant pathogens and human dermatophytes. Furthermore, they were fungicidal against medically important yeasts, showing a most impressive activity against Cryptococcus neoformans, the minimal fungicidal concentration (MFC) value of the gluco derivative of Medicagenic acid, compound G2, is 4 micrograms/ml. The mode of action as well as the structure-activity relationships of these compounds were studied. Compound G2, when applied topically, was effective in curing skin lesions of guinea pigs infected with the dermatophyte Trichophyton mentagrophytes and good skin tolerance to the drug was noted. Furthermore, it had a life-prolonging effect on mice infected with C. neoformans and recently, liposomes containing compound G2 were used efficiently as a drug delivery system in treatment of murine cryptococcosis and candidiosis.
Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra L, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes. Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE.
Medicagenic acid,599-07-5,Castanogenin,Natural Products, buy Medicagenic acid , Medicagenic acid supplier , purchase Medicagenic acid , Medicagenic acid cost , Medicagenic acid manufacturer , order Medicagenic acid , high purity Medicagenic acid
