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Phytic acid sodium salt hydrate

CAS# 14306-25-3

Phytic acid sodium salt hydrate

Catalog No. BCN1283----Order now to get a substantial discount!

Product Name & Size Price Stock
Phytic acid sodium salt hydrate: 5mg $6 In Stock
Phytic acid sodium salt hydrate: 10mg Please Inquire In Stock
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Quality Control of Phytic acid sodium salt hydrate

Number of papers citing our products

Chemical structure

Phytic acid sodium salt hydrate

3D structure

Chemical Properties of Phytic acid sodium salt hydrate

Cas No. 14306-25-3 SDF Download SDF
PubChem ID 66391 Appearance White powder
Formula C6H6Na12O24P6 M.Wt 923.8
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name dodecasodium;(2,3,4,5,6-pentaphosphonatooxycyclohexyl) phosphate
SMILES C1(C(C(C(C(C1OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Standard InChIKey KETSPIPODMGOEJ-UHFFFAOYSA-B
Standard InChI InChI=1S/C6H18O24P6.12Na/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;;;;;;;/q;12*+1/p-12
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Phytic acid sodium salt hydrate

The herbs of Oryza sativa

Biological Activity of Phytic acid sodium salt hydrate

DescriptionPhytic acid sodium salt has inhibitory effect on the activity of the digestive protease and α‐amylase in rohu, Labeo rohita, catla, Catla catla, and mrigal, Cirrhinus mrigala . The sodium salt of phytic acid may have a role in both the prevention and treatment of many forms of cancer.
TargetsSodium Channel | Potassium Channel
In vivo

Modification of N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated urinary bladder carcinogenesis in rats by phytic acid and its salts.[Pubmed: 8045454]

Food Chem Toxicol. 1994 Jun;32(6):499-503.

The effects of dietary phytic acid and its salts(eg. Phytic acid sodium salt hydrate) on the promotion stage of two-stage urinary bladder carcinogenesis were examined.
METHODS AND RESULTS:
Male F344 rats were initiated by exposure to 0.05% N-butyl-N-(4-hydroxybutyl)nitrosamine in the drinking water for 4 wk, and then treated with basal diet containing a 2% supplement of phytic acid (PA), phytic acid dodecasodium salt (Na-PA), phytic acid dodecapotassium salt (K-PA), phytic acid hexamagnesium salt n-hydrate (Mg-PA) or no added chemical for 32 wk. Na-PA significantly increased the development of preneoplastic and neoplastic lesions of the urinary bladder. K-PA also brought about a tendency for increase in papillomas, whereas Mg-PA and PA were without effect. Both Na-PA and K-PA caused elevation of urinary pH, and Na+ or K+ concentration, respectively.
CONCLUSIONS:
These results confirm the promoting activity of the sodium salt of phytic acid for urinary bladder carcinogenesis and indicate modulation by urinary components, as demonstrated by increases in urinary pH, and Na+ concentration.

Phytic acid sodium salt hydrate Dilution Calculator

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Phytic acid sodium salt hydrate Molarity Calculator

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Preparing Stock Solutions of Phytic acid sodium salt hydrate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0825 mL 5.4124 mL 10.8249 mL 21.6497 mL 27.0621 mL
5 mM 0.2165 mL 1.0825 mL 2.165 mL 4.3299 mL 5.4124 mL
10 mM 0.1082 mL 0.5412 mL 1.0825 mL 2.165 mL 2.7062 mL
50 mM 0.0216 mL 0.1082 mL 0.2165 mL 0.433 mL 0.5412 mL
100 mM 0.0108 mL 0.0541 mL 0.1082 mL 0.2165 mL 0.2706 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Phytic acid sodium salt hydrate

Modification of N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated urinary bladder carcinogenesis in rats by phytic acid and its salts.[Pubmed:8045454]

Food Chem Toxicol. 1994 Jun;32(6):499-503.

The effects of dietary phytic acid and its salts on the promotion stage of two-stage urinary bladder carcinogenesis were examined. Male F344 rats were initiated by exposure to 0.05% N-butyl-N-(4-hydroxybutyl)nitrosamine in the drinking water for 4 wk, and then treated with basal diet containing a 2% supplement of phytic acid (PA), phytic acid dodecasodium salt (Na-PA), phytic acid dodecapotassium salt (K-PA), phytic acid hexamagnesium salt n-hydrate (Mg-PA) or no added chemical for 32 wk. Na-PA significantly increased the development of preneoplastic and neoplastic lesions of the urinary bladder. K-PA also brought about a tendency for increase in papillomas, whereas Mg-PA and PA were without effect. Both Na-PA and K-PA caused elevation of urinary pH, and Na+ or K+ concentration, respectively. These results confirm the promoting activity of the sodium salt of phytic acid for urinary bladder carcinogenesis and indicate modulation by urinary components, as demonstrated by increases in urinary pH, and Na+ concentration.

Description

Phytic acid sodium salt (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphat) is often present in legume seeds with antinutritional effects. Phytic acid sodium salt is a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. phytic acid is hydrolyzed by phytases in a stepwise manner in the plant.

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