Picfeltarraegenin ICAS# 82145-63-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 82145-63-9 | SDF | Download SDF |
| PubChem ID | 343254.0 | Appearance | Powder |
| Formula | C30H44O5 | M.Wt | 484.67 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-(3,16-dihydroxy-4,4,9,13,14-pentamethyl-11-oxo-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)-2-methyl-5-propan-2-ylfuran-3-one | ||
| SMILES | CC(C)C1=CC(=O)C(O1)(C)C2C(CC3(C2(CC(=O)C4(C3CC=C5C4CCC(C5(C)C)O)C)C)C)O | ||
| Standard InChIKey | NROSHSGZKWDRMB-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C30H44O5/c1-16(2)20-13-23(33)30(8,35-20)25-19(31)14-27(5)21-11-9-17-18(10-12-22(32)26(17,3)4)29(21,7)24(34)15-28(25,27)6/h9,13,16,18-19,21-22,25,31-32H,10-12,14-15H2,1-8H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Picfeltarraegenin I Dilution Calculator
Picfeltarraegenin I Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0633 mL | 10.3163 mL | 20.6326 mL | 41.2652 mL | 51.5815 mL |
| 5 mM | 0.4127 mL | 2.0633 mL | 4.1265 mL | 8.253 mL | 10.3163 mL |
| 10 mM | 0.2063 mL | 1.0316 mL | 2.0633 mL | 4.1265 mL | 5.1581 mL |
| 50 mM | 0.0413 mL | 0.2063 mL | 0.4127 mL | 0.8253 mL | 1.0316 mL |
| 100 mM | 0.0206 mL | 0.1032 mL | 0.2063 mL | 0.4127 mL | 0.5158 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new cucurbitacin from Picria fel-terrae.[Pubmed:16864449]
J Asian Nat Prod Res. 2006 Jun;8(4):367-71.
A new cucurbitacin, picfeltarraenone II (1) as well as four known cucurbitacins, Picfeltarraegenin I (2), picfeltarraenin IA (3), picfeltarraenin IB (4), and picfeltarraenin IV (5), have been isolated and characterized from the whole plant of Picria fel-terrae. The purity of picfeltarraenin IA has been determined by TLC and HPLC.
Complement-inhibiting cucurbitacin glycosides from Picria fel-terrae.[Pubmed:9644059]
J Nat Prod. 1998 Jun 26;61(6):757-61.
Four cucurbitacin glycosides were isolated from Picriafel-terrae and identified by MS and NMR spectroscopy as picfeltarraenin IA (1), picfeltarraenin IB (2), picfeltarraenin IV (4), and a new compound picfeltarraenin VI (3) (Picfeltarraegenin I 3-O-beta-D-xylopyranoside). All four compounds acted as inhibitors on both the classical and alternative pathways of the complement system, with compound 3 exhibiting the highest inhibitory activity (IC50 29 +/- 2 microM and 21 +/- 1 microM, respectively). Compounds 1-4 showed no antiviral, antibacterial, or antifungal activities. Picfeltarraenin IA and IB were tested in an in vitro human tumor cell line panel, but displayed no cytotoxic activity.
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