Coreoside BCAS# 1580464-83-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 1580464-83-0 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C25H36O12 | M.Wt | 528.55 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Coreoside B Dilution Calculator
Coreoside B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.892 mL | 9.4598 mL | 18.9197 mL | 37.8394 mL | 47.2992 mL |
| 5 mM | 0.3784 mL | 1.892 mL | 3.7839 mL | 7.5679 mL | 9.4598 mL |
| 10 mM | 0.1892 mL | 0.946 mL | 1.892 mL | 3.7839 mL | 4.7299 mL |
| 50 mM | 0.0378 mL | 0.1892 mL | 0.3784 mL | 0.7568 mL | 0.946 mL |
| 100 mM | 0.0189 mL | 0.0946 mL | 0.1892 mL | 0.3784 mL | 0.473 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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The chemical components of Coreopsis tinctoria Nutt. and their antioxidant, antidiabetic and antibacterial activities.[Pubmed:30499349]
Nat Prod Res. 2020 Jun;34(12):1772-1776.
Seventeen compounds were isolated from the capitula of Coreopsis tinctoria Nutt. with various column chromatographic methods and semi-preparative HPLC. Their structures were identified by the spectroscopic data and comparison with literatures as 2'-hydroxy-4,4'-dimethoxy-chalcone; (1), isoliquiritigenin (2), eriodictyol (3), naringenin (4), maritimetin (5), butin (6), taxifolin (7), luteolin (8), 7,3',4'-trihydroxyflavone (9), 8,3',4'-trihydroxyflavone-7-O-beta-d-glucoside (10), quercetin (11), quercetagitin-7-O-beta-d-glucoside (12), quercetin-7-O-beta-d-glucoside (13), 3,4-dihydroxybenzoic acid (14), caffeic acid (15), Coreoside B (16), and myo-inositol (17). Compounds 1, 4, 9, 10 and 17 were isolated from C. tinctoria Nutt. for the first time. Compounds 7 and 12 possessed the highest antioxidant activity (IC(50) = 64.37 and 32.86 microg/ml, respectively) among the tested compounds (IC(50) value of positive control was 5.34 microg/ml). Compound 7 exhibited potent PTP1B enzymatic inhibition with an IC(50) value of 7.73 mug/ml (IC(50) value of positive control is 1.46 microg/ml). Furthermore, compound 5 showed strong antibacterial activity against the Gram-positive bacterium, S. aureus.
Isolation, characterization and antimicrobial activities of polyacetylene glycosides from Coreopsis tinctoria Nutt.[Pubmed:28104231]
Phytochemistry. 2017 Apr;136:65-69.
Polyacetylene glycosides, (6Z, 12E)-tetradecadiene-8,10-diyne-1-ol-3(R)-O-beta-D-glucopyranoside (trivially named coreoside E) and (6Z, 12E)-tetradecadiene-8,10-diyne-1-ol-3(R)-O-beta-L-arabinopyranosyl-(1 --> 2)-beta-D-glucopyranoside (trivially named coreoside F), were isolated from buds of Coreopsis tinctoria Nutt., together with one known compound, Coreoside B. Their chemical structures were elucidated by extensive spectroscopic analysis and on the basis of their chemical reactivities. Coreoside E exhibited high levels of antimicrobial activity against Staphylococcus aureus and Bacillus anthracis with minimum inhibitory concentrations of 27 +/- 0.27 and 18 +/- 0.40 muM, respectively, whereas coreoside F and Coreoside B showed weak antimicrobial activity against S. aureus and B. anthracis.
