Rosin

CAS# 85026-55-7

Rosin

Catalog No. BCN5969----Order now to get a substantial discount!

Product Name & Size Price Stock
Rosin: 5mg $265 In Stock
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Quality Control of Rosin

Number of papers citing our products

Chemical structure

Rosin

3D structure

Chemical Properties of Rosin

Cas No. 85026-55-7 SDF Download SDF
PubChem ID 5280656 Appearance White-yellowish powder
Formula C15H20O6 M.Wt 296.32
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Synonyms Chinese rosin W; Rosin X
Solubility Soluble in ethanol and water
Chemical Name (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol
SMILES C1=CC=C(C=C1)C=CCOC2C(C(C(C(O2)CO)O)O)O
Standard InChIKey KHPCPRHQVVSZAH-GUNCLKARSA-N
Standard InChI InChI=1S/C15H20O6/c16-9-11-12(17)13(18)14(19)15(21-11)20-8-4-7-10-5-2-1-3-6-10/h1-7,11-19H,8-9H2/b7-4+/t11-,12-,13+,14-,15-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rosin

The herb of Rhodiola rosea L.

Biological Activity of Rosin

DescriptionRosin may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.Rosin may cause allergic contact dermatitis in eyeshadow and mascara.
Targetsp38MAPK | pJNK
In vitro

Allergic contact dermatitis due to rosin (colophony) in eyeshadow and mascara[Pubmed: 3229138]

Cutis,1988, 42(6):507-8.

Three patients are reported with allergic reactions to Rosin in eye makeup: two to eyeshadow and one to mascara. In each instance, the dermatitis was bilateral and symmetrical. Several popular eyeshadow and mascara preparations contain Rosin, while the Almay products are free of this ingredient. Rosin-sensitive patients should be instructed to read cosmetic ingredient labels before using any product and should realize that the European term "colophony" is a synonym for Rosin. The numerous products that Rosin-sensitive persons must avoid will be discussed in a future article.

In vivo

Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.[Pubmed: 23690847 ]

Evid Based Complement Alternat Med. 2013;2013:514049.


METHODS AND RESULTS:
To determine the biological activity of Rhodiola rosea, the protein expression of iNOS and proinflammatory cytokines was measured after the activation of murine microglial BV2 cells by LPS under the exposure of constituents of Rhodiola rosea: crude extract, Rosin, Rosarin, and salidroside (each 1-50  μ g/mL). The LPS-induced expression of iNOS and cytokines in BV2 cells was suppressed by the constituents of Rhodiola rosea in a concentration-dependent manner. Also the expression of the proinflammatory factors iNOS, IL-1 β , and TNF- α in the kidney and prefrontal cortex of brain in mice was suppressed by the oral administration of Rhodiola rosea crude extract (500 mg/kg). To determine the neuroprotective effect of constituents of Rhodiola rosea, neuronal cells were activated by L-glutamate, and neurotoxicity was analyzed. The L-glutamate-induced neurotoxicity was suppressed by the treatment with Rosin but not by Rosarin. The level of phosphorylated MAPK, pJNK, and pp38 was increased by L-glutamate treatment but decreased by the treatment with Rosin and salidroside.
CONCLUSIONS:
These results indicate that Rhodiola rosea may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.

Rosin Dilution Calculator

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Rosin Molarity Calculator

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Preparing Stock Solutions of Rosin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3747 mL 16.8737 mL 33.7473 mL 67.4946 mL 84.3683 mL
5 mM 0.6749 mL 3.3747 mL 6.7495 mL 13.4989 mL 16.8737 mL
10 mM 0.3375 mL 1.6874 mL 3.3747 mL 6.7495 mL 8.4368 mL
50 mM 0.0675 mL 0.3375 mL 0.6749 mL 1.3499 mL 1.6874 mL
100 mM 0.0337 mL 0.1687 mL 0.3375 mL 0.6749 mL 0.8437 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rosin

Allergic contact dermatitis due to rosin (colophony) in eyeshadow and mascara.[Pubmed:3229138]

Cutis. 1988 Dec;42(6):507-8.

Three patients are reported with allergic reactions to Rosin in eye makeup: two to eyeshadow and one to mascara. In each instance, the dermatitis was bilateral and symmetrical. Several popular eyeshadow and mascara preparations contain Rosin, while the Almay products are free of this ingredient. Rosin-sensitive patients should be instructed to read cosmetic ingredient labels before using any product and should realize that the European term "colophony" is a synonym for Rosin. The numerous products that Rosin-sensitive persons must avoid will be discussed in a future article.

Description

Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis.

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