Neuroscience Research

Neuroscience is the study of the nervous system - one of the major mammalian systems responsible for sustaining life. The central nervous system (CNS) and peripheral nervous system (PNS) work in concert to coordinate basic functions such as moving and breathing, as well as 'higher order' functions including thought, speech and emotion.

Neuroscience Research Products Areas

Products for Neuroscience Research - Page 39

Cat.No. Product Name Information/Activity
BCC7236 SKF 86002 dihydrochloride 116339-68-5
BCC4961 Suplatast Tosylate Suplatast Tosilate (IPD 1151T) is a Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.
BCC2248 Thalidomide Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.
BCC3931 Trovafloxacin mesylate Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1.
BCC1245 10Panx Panx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions
BCC1246 Scrambled 10Panx Scrambled version of <sup>10</sup>Panx, Panx-1 mimetic inhibitory peptide
BCC3745 Carbenoxolone disodium 7421-40-1
BCC1032 Gap 26 Gap 26 is a connexin mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
BCC1033 Gap 27 Gap 27, connexin43 mimetic peptide, is a gap junction inhibitor.
BCC5599 Gap19 Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial.