Alzheimer's Disease Research

Alzheimer's disease (AD), the most common type of dementia, is an irreversible and progressive neurodegenerative disorder causing cognitive and functional impairment. It is characterized by formation of protein aggregates and progressive loss of neurons in the central nervous system (CNS). The symptoms of AD include short-term memory loss, confusion, irritability, aggression and mood swings, progressing to long-term memory deficit, withdrawal from social interactions and subsequently a loss in higher central functioning.

Alzheimer's Disease Research Products Targets

Products for Alzheimer's Disease Research - Page 26

  1. Cat.No. Product Name Information/Activity
  2. BCC7535 NS 1738 NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nAChR, with respect to positive modulation of α7 nAChR (EC50=3.4 μM in oocyte experiments). NS 1738 chemical structure
  3. BCC4581 PNU-120596 PNU-120596 (NSC 216666 ) is a potent and selective positive allosteric α7 nAChR modulator with an EC50 of 0.2 μM. PNU-120596 chemical structure
  4. BCC7896 TQS 353483-92-8 TQS chemical structure
  5. BCC7564 FR 236924 DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. FR 236924 chemical structure
  6. BCC6926 (RS)-AMPA hydrobromide 171259-81-7 (RS)-AMPA hydrobromide chemical structure
  7. BCC6582 (R)-AMPA 83654-13-1 (R)-AMPA chemical structure
  8. BCC6560 (RS)-AMPA 74341-63-2 (RS)-AMPA chemical structure
  9. BCC6583 (S)-AMPA 83643-88-3 (S)-AMPA chemical structure
  10. BCC7147 Cl-HIBO 909400-43-7 Cl-HIBO chemical structure
  11. BCC7106 (S)-CPW 399 389888-02-2 (S)-CPW 399 chemical structure

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