Alzheimer's Disease Research
Alzheimer's disease (AD), the most common type of dementia, is an irreversible and progressive neurodegenerative disorder causing cognitive and functional impairment. It is characterized by formation of protein aggregates and progressive loss of neurons in the central nervous system (CNS). The symptoms of AD include short-term memory loss, confusion, irritability, aggression and mood swings, progressing to long-term memory deficit, withdrawal from social interactions and subsequently a loss in higher central functioning.
Alzheimer's Disease Research Products Targets
- Others (23)
- Cyclooxygenase (24)
- Complement (2)
- AMPA Receptor (45)
- Nicotinic (α7) Receptor (25)
- Nicotinic (α4β2) Receptor (14)
- NMDA Receptor (87)
- Kainate Receptor (22)
- Microtubule (19)
- DYRK (3)
- Cholinesterase (10)
- Autophagy (44)
- Antioxidant (19)
- Amyloid beta Peptide (28)
- Estrogen and Related Receptor (33)
- Glycogen Synthase Kinase 3 (20)
- gamma-Secretase (9)
Products for Alzheimer's Disease Research - Page 26
- Cat.No. Product Name Information/Activity
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BCC7535
NS 1738
NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nAChR, with respect to positive modulation of α7 nAChR (EC50=3.4 μM in oocyte experiments).
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BCC4581
PNU-120596
PNU-120596 (NSC 216666 ) is a potent and selective positive allosteric α7 nAChR modulator with an EC50 of 0.2 μM.
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BCC7896
TQS
353483-92-8
-
BCC7564
FR 236924
DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε.
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BCC6926
(RS)-AMPA hydrobromide
171259-81-7
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BCC6582
(R)-AMPA
83654-13-1
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BCC6560
(RS)-AMPA
74341-63-2
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BCC6583
(S)-AMPA
83643-88-3
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BCC7147
Cl-HIBO
909400-43-7
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BCC7106
(S)-CPW 399
389888-02-2


