Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 48

  1. Cat.No. Product Name Information/Activity
  2. BCC6933 Charybdotoxin 95751-30-7 Charybdotoxin chemical structure
  3. BCC6932 Iberiotoxin 129203-60-7 Iberiotoxin chemical structure
  4. BCC7710 Kaliotoxin 145199-73-1 Kaliotoxin chemical structure
  5. BCC6307 NS 6180 NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation. NS 6180 chemical structure
  6. BCC1122 TRAM-34 TRAM-34 is a highly selective blocker of intermediate-conductance calcium-activated K+ channel (IKCa1) (Kd=20 nM). TRAM-34 chemical structure
  7. BCC8038 TRAM 39 Potent K<sub>Ca</sub>3.1 blocker TRAM 39 chemical structure
  8. BCC7016 UCL 1684 199934-16-2 UCL 1684 chemical structure
  9. BCC7446 UCL 2077 UCL 2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker (IC50 = 500 nM in hippocampal neurons in culture), having minimal effects on Ca2+ channels, action potentials, input resistance and the medium after hyperpolarization. UCL 2077 is also a subtype-selective blocker of the epilepsy associated KCNQ channels. UCL 2077 chemical structure
  10. BCC7038 Cromakalim 94470-67-4 Cromakalim chemical structure
  11. BCC7039 Levcromakalim Levcromakalim ((-)-Cromakalim) is an ATP-sensitive K+ channel (KATP) activator. Levcromakalim chemical structure

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