BCC2008
Toltrazuril sulfone
Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites.
BCC4231
Pefloxacin
Pefloxacin is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections.
BCC4821
Pefloxacin Mesylate
Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections.
BCC4688
Norfloxacin
Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
BCC4033
Tilbroquinol
Tilbroquinol is an antiprotozoal agent effective against amoebiasis. It has also been used against Vibrio cholerae.
BCC1381
Avermectin B1
Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
BCC5274
Ceftazidime
Ceftazidime (GR20263) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases.
BCC4936
Rifabutin
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
BCC5212
Niclosamide monohydrate
Niclosamide monohydrate is an inhibitor of <b>STAT</b> with <b>IC<sub>50</sub></b> of 0.7 μM and inhibits DNA replication in a cell-free assay.
BCC5195
Ethambutol
Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
BCC3775
Enoxacin (Penetrex)
Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
BCC6446
Solithromycin
Solithromycin (CEM-101) is an orally bioavailable, effective antimicrobial agent, with IC50s for inhibition of cell viability, protein synthesis, and growth rate are 7.5 ng/mL, 40 ng/mL, and 125 ng/mL for Streptococcus pneumonia, Staphylococcus aureus, and Haemophilus influenzae, respectively. Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis.
BCC1392
Azathramycin
Azathramycin (Azaerythromycin A) is an antibiotic.
BCN2216
Pimaricin
Natamycin (pimaricin) is an antifungal macrolide polyene that binds to cell membrane sterols.
BCC2557
Aztreonam
Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).
BCC4889
Amorolfine HCl
Amorolfine hydrochloride (Ro 14-4767/002) is a antifungal reagent.
BCC4819
Oxytetracycline (Terramycin)
Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity.
BCC5220
Dapsone
Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.
BCC4916
Loteprednol etabonate
Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology.
BCC4385
Azithromycin
Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
BCC5246
Bedaquiline
Bedaquiline (TMC207) is a diarylquinoline drug and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-drug resistant tuberculosis.
BCC5245
Bedaquiline fumarate
Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
BCC4914
Itraconazole
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects.
BCC1990
Tedizolid
Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
BCC4905
Fluconazole
Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
BCC5201
Mc-MMAE
Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a drug-linker conjugate for ADC.
BCC1882
Radezolid
Radezolid is a novel oxazolidinone antibiotic agent.
BCC5156
Walrycin B
Walrycin B is a novel antibacterial compound specifically targeting the essential WalR response regulator.
BCC5437
Buparvaquone
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone.
BCC5407
AVX 13616
AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens.
BCC3865
Terbinafine
Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria.
BCC3747
Cefdinir
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic, which is proved to be effective for common bacterial infections of the ear, sinus, throat, and skin.
BCC2489
Meropenem
Meropenem (SM 7338) is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity.
BCC5216
Ceftibuten
Ceftibuten(Sch39720) is a third-generation cephalosporin antibiotic.
BCC4932
Pyrazinamide
Pyrazinamide is a pyrazine that is used therapeutically as an antitubercular agent.