Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN2405 Magnoflorine chloride
Magnoflorine is usually used as an anxiolytic chemical with anti-oxidant, α-tyrosinase inhibitory and anti-inflammationary activities.
BCN2406 Isosilybin
Isosilybin and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patients.
BCN2407 Acetylaconitine
3-Acetylaconitine, aconitine, and deoxyaconitine are main toxic components of the roots of Aconitum pendulum.
BCN2408 Safflor Yellow A
1. Safflor Yellow A protects cultured rat cardiomyocytes against A/R injury, maybe via inhibiting cellular oxidative stress and apoptosis.
BCN2409 Lycorine
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.Lycorine has antiviral, and anti-cancer effects, the mechanisms of Lycorine on the multiple myeloma cell line ARH-77 are associated with G1 phase cell cycle arrest, mitochondrial dysfunction, reactive oxygen species (ROS) generation, ATP depletion, and DNA damage.
BCN2410 Cyclo(Ile-Val)
Cyclo(Ile-Val) shows moderate antifungal and weak antitumor activities in vitro.
BCN6377 3'-Methoxymirificin
Cyclo(Val-Hpro) is isolated from Ascotricha genus.
BCN2411 Cyclo(Ala-Phe)
Cyclo(Phe-Ala) displays significant anti-diatom activity with the inhibitory rate of 50% at the concentration of 50 microg/mL.