Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 665 - 672 of 9359 hot products
| Catalog No. | Product Name |
|---|---|
| BCC3798 | Istradefylline (KW-6002) |
|
Potent and selective adenosine A2A receptor antagonist (Ki values are 2.2 and 150 nM for A2A and A1 receptors respectively). Anticataleptic and antiparkinson agent; reverses drug-induced motor dysfunction in animal models.
|
|
| BCC3799 | Nilvadipine |
|
Syk inhibitor. Blocks A<span class='symbol'>β</span> production, APP<span class='symbol'>β</span> secretion and reduces BACE-1 expression in CHO cells over-expressing A<span class='symbol'>β</span> <em>in vitro</em>. Enhances clearance of A<span class='symbol'>β</span> across the blood brain barrier <em> in vivo</em>. Reduces brain A<span class='symbol'>β</span> levels in a mouse tauopathy model. Also L-type calcium channel blocker and antihypertensive.
|
|
| BCC3800 | JTC-801 |
|
High affinity, selective NOP receptor antagonist (K<sub>i</sub> = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human <span class='symbol'>μ</span>-, <span class='symbol'>κ</span>- and <span class='symbol'>δ</span>-opioid receptors respectively. Exhibits anti-nociceptive effects in acute pain models <em>in vivo</em>. Orally active.
|
|
| BCC3802 | Laquinimod (ABR-215062) |
|
Laquinimod is an orally-available. quinolinone-based, broad spectrum immunomodulator with anti-inflammatory activity
|
|
| BCC3804 | Lithium Citrate |
|
Citric acid trilithium salt tetrahydrate is a pharmaceutical and construction material, used in HPLC gradient elution for quantitative amino acid analysis.
|
|
| BCC3805 | Lithocholic Acid |
|
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.Lithocholic acid is a vitamin D receptor (VDR) ligand, it can activate the VDR to block inflammatory signals in colon cells.
|
|
| BCC3819 | Noscapine HCl |
|
Opioid alkaloid with several actions. Binds to tubulin, arrests cells in mitosis and induces apoptosis. Antagonist at bradykinin receptors (pA<sub>2</sub> = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Modulates IKK activation, suppressing the NF-<span class='symbol'>κ</span>B signaling pathway. Blocks proliferation of human leukemia and multiple myeloma cells. Exhibits anti-inflammatory activity.
|
|
| BCC3821 | Nicotine Difartrate |
|
Nicotinic acetylcholine receptor (nAChR) agonist (K<sub>i</sub> values are 1, > 1000, 4000 and 7130 nM at <span class='symbol'>α</span>4<span class='symbol'>β</span>2, <span class='symbol'>α</span>1<span class='symbol'>β</span>1<span class='symbol'>δ</span><span class='symbol'>γ</span>, rat <span class='symbol'>α</span>7 and human <span class='symbol'>α</span>7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity <em>in vivo</em>.
|
|