Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2433 | Cyclo(Leu-Leu) |
| Cyclo(Leu-Leu) is an efficient supramolecular catalyst. | |
| BCN2434 | Cyclo(Ile-Leu) |
| Cyclo(Ile-Leu) shows cytotoxic activity in vitro. | |
| BCN2436 | Cyclo(Leu-Val) |
| Cyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain. | |
| BCN2437 | Ganoderic acid D |
| Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(50) value of 17.3 +/- 0.3 microM. | |
| BCN2438 | Ganoderic acid N |
| 1. 23-Dihydroganoderic Acid N has anticancer effects. | |
| BCN2439 | Ganoderic acid Y |
| 1. Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating. | |
| BCN2440 | Ganoderic acid Z |
| 1. Ganoderic acid zeta has cytotoxicity in vitro against Meth-A and LLC cell lines. 2. The binding affinities of ganoderic acid DM and Z (ΔGbind, −16.83 and−10.99 kcal mol−1) are comparable to that of current commercial drug oseltamivir (−23.62 kcal mol−1);Ganoderic acid DM is a potential source of anti-influenza ingredient, with novel binding pattern and advantage over oseltamivir, it has steric hindrance on the 150 cavity of N1 protein, and exerts activities across the H274Y and N294S mutations, is the attractive candidates of novel neuraminidase (NA) inhibitors. | |
| BCN2441 | Ganoderic acid AM1 |
| 1. Ganoderic acid AM1 treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.8+/-0.7 microM. | |
