Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 713 - 720 of 9359 hot products
| Catalog No. | Product Name |
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| BCC3915 | Chloroquine diphosphate |
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Antimalarial drug. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro. Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine.
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| BCC3916 | DBeQ |
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Selective and reversible inhibitor of p97 ATPase (IC<sub>50</sub> = 1.5 <span class='symbol'>μ</span>M). Induces executioner caspases (caspase-3 and caspase-7) rapidly. Blocks the degradation of endoplasmic reticulum-associated degradation (ERAD) reporters; also blocks autophagosome maturation and promotes accumulation of LC3-II.
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| BCC3917 | 8'-Epicleomiscosin A |
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8'-Epicleomiscosin A shows strong inhibition (IC50=1.33 microM) against the enzyme tyrosinase, as compared to the standard tyrosinase inhibitors kojic acid (IC50=16.67 microM) and L-mimosine (IC50=3.68 microM), indicating its potential used for the treatment of hyperpigmentation associated with the high production of melanocytes.
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| BCC3918 | (±)-Bay K 8644 |
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L-type Ca<sup>2+</sup> channel activator (EC<sub>50</sub> = 17.3 nM). Has positive inotropic, vasoconstrictive and behavioral effects <em>in vivo</em>. Separate enantiomers (<em>R</em>)-(+)-Bay K 8644</a> and (<em>S</em>)-(-)-Bay K 8644</a> also available. In combination with BIX-01294, helps generate induced pluripotent stem cells (iPSCs) from mouse embryonic fibroblasts (MEFs). Inhibits autophagy.
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| BCC3919 | Concanamycin A |
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Specific inhibitor of V-type (vacuolar) H<sup>+</sup>-ATPase that displays > 2000-fold selectivity over other H<sup>+</sup>-ATPases (IC<sub>50</sub> values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H<sup>+</sup>-ATPases and porcine P-type Na<sup>+</sup>,K<sup>+</sup>-ATPase respectively). Blocks cell surface expression of virus envelope glycoproteins without affecting synthesis and exhibits cytotoxicity in several cell lines.
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| BCC3925 | Flavopiridol hydrochloride |
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Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G<sub>1</sub> and G<sub>2</sub> phase. Potently inhibits the growth of breast and lung cancer cell lines (IC<sub>50</sub> = 25 - 160 nM) <em>in vitro</em>.
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| BCC3929 | Acyclovir |
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Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC<sub>50</sub> values are 0.85 and 0.86 <span class='symbol'>μ</span>M respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).
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| BCC3930 | Viomycin |
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Member of the tuberactinomycin family of antibiotics. Inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational state. Facilitates <em>trans</em>-cleavage of the <em>Neurospora</em> VS ribozyme.
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