Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 649 - 656 of 9359 hot products
| Catalog No. | Product Name |
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| BCC3745 | Carbenoxolone disodium |
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Glucocorticoid that inhibits 11<span class='symbol'>β</span>-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication.
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| BCC3755 | Clotrimazole |
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Imidazole antimycotic and cytochrome P450 inhibitor. Inhibits Ca<sup>2+</sup>-activated K<sup>+</sup> current (IC<sub>50</sub> = 3 <span class='symbol'>μ</span>M) and L-type Ca<sup>2+</sup> current; increases the firing rate of action potentials. Exhibits antiproliferative activity <em>in vitro</em> and <em>in vivo</em>. Also an inverse agonist of the human constitutive androstane receptor (hCAR).
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| BCC3759 | Cytarabine |
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Nucleoside analog of deoxycytidine; inhibits DNA replication by incorporating into DNA (IC<sub>50</sub> = 0.04 <span class='symbol'>μ</span>M in L1210 and CEM cell lines). Displays no inhibitory effects on RNA synthesis. Causes S phase cell cycle arrest in ML-1 cell lines; cytotoxic in L5817Y leukemia cells. Antineoplastic and antileukemic agent.
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| BCC3768 | Diphenylpyraline HCl |
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Diphenylpyraline Hcl is a first-generation antihistamine with anticholinergic effects, acts as a dopamine reuptake inhibitor, shows to be useful in the treatment of Parkinsonism.
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| BCC3770 | Dofetilide |
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Selective potassium channel blocker. Blocks KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr). Displays class III antiarrhythmic properties.
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| BCC3773 | Duloxetine HCl |
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High affinity, competitive 5-HT and noradrenaline (NA) re-uptake inhibitor (Ki values are 8.5 and 45 nM for 5-HT and NA reuptake respectively in cortical synaptosomes; IC50 values are 28 and 46 nM for 5-HT and NA reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki = 300 nM in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable.
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| BCC3776 | Epleremone |
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Selective mineralocorticoid (aldosterone) receptor antagonist (IC<sub>50</sub> = 360 nM). Displays > 27-fold selectivity over androgen, progesterone and estrogen receptors (IC<sub>50</sub> > 10 <span class='symbol'>μ</span>M). Orally active antihypertensive <em>in vivo</em>.
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| BCC3779 | Famprofazone |
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Famprofazone is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series, has analgesic, anti-inflammatory, and antipyretic effects.
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