BCN4921BarbacarpanBotanical source: The herbs of Crotalaria barbata(CAS NO.:213912-46-0)
BCN6799Chrysin dimethylether5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor.(CAS NO.:21392-57-4)
BCN4925AgrimonolideBotanical source: The herb of Agrimonia pilosa Ledeb.(CAS NO.:21499-24-1)
BCN46747,3',4'-TrihydroxyflavoneBotanical source: The seeds of Cassia occidentalis(CAS NO.:2150-11-0)
BCN2891SophoflavescenolSophoflavescenol is a prenylated flavonol, which shows great inhibitory activity with IC50 of 0.013 μM against Phosphodiesterase 5 (PDE5), and also inhibits RLAR, HRAR, AGE, BACE1, AChE and BChE with IC50s of 0.30 µM, 0.17 µM, 17.89 µg/mL, 10.98 µM, 8.37 µM and 8.21 µM, respectively.(CAS NO.:216450-65-6)
BCN29585-O-Demethylnobiletin5-O-Demethylnobiletin (5-Demethylnobiletin), a polymethoxyflavone isolated from Sideritis tragoriganum, is a direct inhibition of 5-LOX (IC50=0.1 μM), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 μM.(CAS NO.:2174-59-6)
BCN40823'-MethoxydaidzeinBotanical source: The herbs of Derris robusta(CAS NO.:21913-98-4)
BCN37584',7-Dihydroxyflavone7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM.(CAS NO.:2196-14-7)
BCN5901BaicalinBaicalin is a flavonoid glycoside isolated from Scutellaria baicalensis. Baicalin reduces the expression of NF-κB.(CAS NO.:21967-41-9)