BCN6316Procyanidin B3Procyanidin B3 is a natural product, acts as a specific HAT inhibitor, binds to the other site of p300 instead of the active site, selectively inhibits p300-mediated androgen receptor acetylation. Procyanidin B3 has no effect on HDAC or HMT (histone methyltransferase).(CAS NO.:23567-23-9)
BCN5089PutraflavoneBotanical source: The leaves of Ginkgo biloba L.(CAS NO.:23624-21-7)
BCN3013Vicenin -2Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium.(CAS NO.:23666-13-9)
BCN2481FarrerolFarrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects.(CAS NO.:24211-30-1)
BCN8125Hesperidin methylchalconeHesperidin methylchalcone (Hesperidin methyl chalcone) inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone inhibits inflammation and pain. Hesperidin methylchalcone exhibits vasoprotective activity.(CAS NO.:24292-52-2)
BCN3955Derrisisoflavone BBotanical source: The herbs of Derris robusta(CAS NO.:246870-75-7)
BCN5114(-)-EpiafzelechinBotanical source: The herbs of Celastrus orbiculatus(CAS NO.:24808-04-6)
BCN5121(+)-AfzelechinBotanical source: The herbs of Celastrus orbiculatus(CAS NO.:2545-00-8)
BCN3307Kushenol WBotanical source: The roots of Sophora flavescens Ait.(CAS NO.:254886-76-5)
BCN3350Kushenol XBotanical source: The roots of Sophora flavescens Ait.(CAS NO.:254886-77-6)
BCN8266LonicerinLonicerin is an anti-algE (alginate secretion protein) flavonoid with inhibitory activity for P. aeruginosa. Lonicerin prevents inflammation and apoptosis in LPS-induced acute lung injury.(CAS NO.:25694-72-8)
BCN5130VelutinVelutin is an aglycone extracted from Korean Mistletoe, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway.(CAS NO.:25739-41-7)
BCN2370LigustroflavoneLigustroflavone, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice.(CAS NO.:260413-62-5)
BCN3846SotetsuflavoneSotetsuflavone is a potent inhibitor of DENV-NS5 RdRp (Dengue virus NS5 RNA-dependent RNA polymerase) with an IC50 of 0.16 uM, is the most active compound of this series .(CAS NO.:2608-21-1)
BCN78836-PrenylsakuranetinBotanical source: The leaves of Oryza sativa L.(CAS NO.:261776-61-8)
BCN6853Taiwanhomoflavone ABotanical source: The stems of Cephalotaxus wilsoniana.(CAS NO.:265120-00-1)
BCN2311ApiinApiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells.(CAS NO.:26544-34-3)
BCN29862'-Methoxykurarinone(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells.(CAS NO.:270249-38-2)
BCN5160AmpelopsinDihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2).(CAS NO.:27200-12-0)
