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Four children have remained free of detectable HIV for over a year after pausing their antiretroviral therapy (ART), as presented at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver. These children, who were born with HIV, participated in a National Institutes of Health-funded clinical trial where ART was initiated within 48 hours of birth. The trial monitored drug safety and HIV viral suppression, and the recent outcomes follow planned ART interruptions once the children met specific virological and immunological criteria. Dr. Jeanne Marrazzo, Director of NIAID, highlighted the significance of these findings, stating, "These findings are clear evidence th ……view more

An experimental cancer drug might offer a new way to clear HIV from infected brain cells, according to a recent study by Tulane University. Researchers at the Tulane National Primate Research Center have, for the first time, demonstrated that this drug can significantly reduce levels of Simian Immunodeficiency Virus (SIV)—the primate equivalent of HIV—in the brain. The drug achieves this by targeting and depleting specific immune cells that serve as reservoirs for the virus. A groundbreaking study published in the journal *Brain* has unveiled a promising new approach to eliminating HIV from hard-to-reach reservoirs, where the virus often evades conventional treatments. Th ……view more