Flemiphilippinin ACAS# 140366-64-9 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 140366-64-9 | SDF | Download SDF |
| PubChem ID | 10074228 | Appearance | Powder |
| Formula | C30H32O6 | M.Wt | 488.58 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 7-(3,4-dihydroxyphenyl)-5-hydroxy-2,2-dimethyl-3-(2-methylbut-3-en-2-yl)-10-(3-methylbut-2-enyl)pyrano[3,2-g]chromen-6-one | ||
| SMILES | CC(=CCC1=C2C(=C(C3=C1OC=C(C3=O)C4=CC(=C(C=C4)O)O)O)C=C(C(O2)(C)C)C(C)(C)C=C)C | ||
| Standard InChIKey | VBTMMYSERQFPPK-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C30H32O6/c1-8-29(4,5)23-14-19-25(33)24-26(34)20(17-10-12-21(31)22(32)13-17)15-35-28(24)18(11-9-16(2)3)27(19)36-30(23,6)7/h8-10,12-15,31-33H,1,11H2,2-7H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Flemiphilippin A has antioxidant activity, it shows DPPH radical scavenging activity with effective half maximal concentration (EC50) of 18.36 ug/mL. 2. Flemiphilippinin A (5 ug/mL) exhibits some level of antitumor activity against human hepatocellular carcinoma cell (BEL-7402), human lung epithelial (A-549) and human ileocecal adenocarcinoma cell (HCT-8). |
Flemiphilippinin A Dilution Calculator
Flemiphilippinin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0467 mL | 10.2337 mL | 20.4675 mL | 40.935 mL | 51.1687 mL |
| 5 mM | 0.4093 mL | 2.0467 mL | 4.0935 mL | 8.187 mL | 10.2337 mL |
| 10 mM | 0.2047 mL | 1.0234 mL | 2.0467 mL | 4.0935 mL | 5.1169 mL |
| 50 mM | 0.0409 mL | 0.2047 mL | 0.4093 mL | 0.8187 mL | 1.0234 mL |
| 100 mM | 0.0205 mL | 0.1023 mL | 0.2047 mL | 0.4093 mL | 0.5117 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Magnaldehyde B
Catalog No.:BCN8677
CAS No.:92829-72-6
- Lappaol C
Catalog No.:BCN8676
CAS No.:64855-00-1
- 13-Methylberberine
Catalog No.:BCN8675
CAS No.:54260-72-9
- Aurantio-obtusin beta-D-glucoside
Catalog No.:BCN8674
CAS No.:129025-96-3
- Pomiferin
Catalog No.:BCN8673
CAS No.:572-03-2
- Resveratroloside
Catalog No.:BCN8672
CAS No.:38963-95-0
- Epimagnolin B
Catalog No.:BCN8671
CAS No.:1134188-26-3
- Moscatin
Catalog No.:BCN8670
CAS No.:108335-06-4
- Ophiopogonanone B
Catalog No.:BCN8669
CAS No.:1316759-83-7
- 4''-methyloxy-Genistin
Catalog No.:BCN8668
CAS No.:950910-16-4
- 4''-methyloxy-Daidzin
Catalog No.:BCN8667
CAS No.:1195968-02-5
- Lappaol F
Catalog No.:BCN8665
CAS No.:69394-17-8
- Kudinoside D
Catalog No.:BCN8679
CAS No.:173792-61-5
- Perisesaccharide C
Catalog No.:BCN8680
CAS No.:1311473-28-5
- Cafestol
Catalog No.:BCN8681
CAS No.:469-83-0
- Huzhangoside B
Catalog No.:BCN8682
CAS No.:94795-70-7
- Protohypericin
Catalog No.:BCN8683
CAS No.:548-03-8
- Glabrol
Catalog No.:BCN8684
CAS No.:59870-65-4
- Isolindleyin
Catalog No.:BCN8685
CAS No.:87075-18-1
- Isopropyl ferulate
Catalog No.:BCN8686
CAS No.:59831-94-6
- Licochalcone D
Catalog No.:BCN8687
CAS No.:144506-15-0
- Licochalcone E
Catalog No.:BCN8688
CAS No.:864232-34-8
- Conicasterol
Catalog No.:BCN8689
CAS No.:76758-18-4
- Clematichinenoside AR
Catalog No.:BCN8690
CAS No.:761425-93-8
Ultrasonic-Assisted Extraction and Evaluation of Biological Activities of Flavonoids from Flemingia philippinensis Merr et Rolfe.
Tropical Journal of Pharmaceutical Research, 2015, 14(8):1365.
To develop a simple and rapid method for extracting total flavonoids from the roots of Flemingia philippinensis and to investigate the antioxidant and anti-tumor activities of the extracts of the materials from various locations in China. Methods: The total flavonoids in F. philippinensis were obtained by ultrasonic-assisted conventional solvent extraction method, and the extraction conditions were optimized by single factor and orthogonal test. 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and anti-tumor activities, using 3-(4,5- dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, of the extract were evaluated. The contents of Flemiphilippinin A, auriculasin, 5,7,3′,4′-tetrahydroxy-6,8 -diprenylisoflavone and dorsmanins I were also determined. Results: Optimal extraction conditions were as follows: extraction time, 40 min; methanol concentration, 85 %; and solvent to solid ratio, 40 mL/g; and number of extraction, once. Total flavonoid content varied greatly (3.7 - 14.35 %) among the 19 samples collected from different origins in China. Flemiphilippin A, 5,7,3′,4′- tetrahydroxy-6,8 -diprenylisoflavone, auriculasin and dorsmanins I showed varying DPPH radical scavenging activities with effective half maximal concentration (EC50) of 18.36, 23.59, 57.25 and 63.54 μg/mL, respectively. Flemiphilippinin A (5 μg/mL) also exhibited some level of antitumor activity against human hepatocellular carcinoma cell (BEL-7402), human lung epithelial (A-549) and human ileocecal adenocarcinoma cell (HCT-8) with inhibition of 91.13 ± 1.6, 91.22 ± 3.23, and 79.77 ± 3.57 %, respectively. Conclusion: Total flavonoids can be extracted efficiently from F. philippinensis by ultrasonic-assisted extraction method. Flemiphilippinin A has a potential for use in medicine as an antioxidant and antitumor drug.
