H-Arg-OH.HCl

CAS# 1119-34-2

H-Arg-OH.HCl

2D Structure

Catalog No. BCC2857----Order now to get a substantial discount!

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H-Arg-OH.HCl

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Chemical Properties of H-Arg-OH.HCl

Cas No. 1119-34-2 SDF Download SDF
PubChem ID 66250 Appearance Powder
Formula C6H15ClN4O2 M.Wt 210.7
Type of Compound N/A Storage Desiccate at -20°C
Synonyms (S)-(+)-Arginine hydrochloride
Solubility H2O : ≥ 100 mg/mL (474.70 mM)
*"≥" means soluble, but saturation unknown.
Chemical Name (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride
SMILES C(CC(C(=O)O)N)CN=C(N)N.Cl
Standard InChIKey KWTQSFXGGICVPE-WCCKRBBISA-N
Standard InChI InChI=1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of H-Arg-OH.HCl

DescriptionL-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Target: Others Arginine is an α-amino acid. It was first isolated in 1886. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice.

References:
[1]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [2]. Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12. [3]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17.

H-Arg-OH.HCl Dilution Calculator

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H-Arg-OH.HCl Molarity Calculator

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Preparing Stock Solutions of H-Arg-OH.HCl

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7461 mL 23.7304 mL 47.4608 mL 94.9217 mL 118.6521 mL
5 mM 0.9492 mL 4.7461 mL 9.4922 mL 18.9843 mL 23.7304 mL
10 mM 0.4746 mL 2.373 mL 4.7461 mL 9.4922 mL 11.8652 mL
50 mM 0.0949 mL 0.4746 mL 0.9492 mL 1.8984 mL 2.373 mL
100 mM 0.0475 mL 0.2373 mL 0.4746 mL 0.9492 mL 1.1865 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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H-Arg-OH.HCl

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Description

L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

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