Sikokianin ACAS# 106293-99-6 |
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| Cas No. | 106293-99-6 | SDF | Download SDF |
| PubChem ID | 21636083 | Appearance | Powder |
| Formula | C31H24O10 | M.Wt | 556.5 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S,3S)-3-[(2S,3S)-5,7-dihydroxy-2-(4-methoxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one | ||
| SMILES | COC1=CC=C(C=C1)C2C(C(=O)C3=C(C=C(C=C3O2)O)O)C4C(OC5=CC(=CC(=C5C4=O)O)O)C6=CC=C(C=C6)O | ||
| Standard InChIKey | QOPUSVUZHPIYER-GERHYJQASA-N | ||
| Standard InChI | InChI=1S/C31H24O10/c1-39-19-8-4-15(5-9-19)31-27(29(38)25-21(36)11-18(34)13-23(25)41-31)26-28(37)24-20(35)10-17(33)12-22(24)40-30(26)14-2-6-16(32)7-3-14/h2-13,26-27,30-36H,1H3/t26-,27-,30-,31-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Stellera chamaejasme Linn.
| Description | 1. Sikokianin A shows in vitro antiviral activity against HBsAg secretion. |
| Targets | HBV |
Sikokianin A Dilution Calculator
Sikokianin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.7969 mL | 8.9847 mL | 17.9695 mL | 35.9389 mL | 44.9236 mL |
| 5 mM | 0.3594 mL | 1.7969 mL | 3.5939 mL | 7.1878 mL | 8.9847 mL |
| 10 mM | 0.1797 mL | 0.8985 mL | 1.7969 mL | 3.5939 mL | 4.4924 mL |
| 50 mM | 0.0359 mL | 0.1797 mL | 0.3594 mL | 0.7188 mL | 0.8985 mL |
| 100 mM | 0.018 mL | 0.0898 mL | 0.1797 mL | 0.3594 mL | 0.4492 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Biflavanones, flavonoids, and coumarins from the roots of Stellera chamaejasme and their antiviral effect on hepatitis B virus.[Pubmed:18649308]
Chem Biodivers. 2008 Jul;5(7):1419-24.
A new 3,3''-biflavanone, isoSikokianin A, was isolated from the roots of Stellera chamaejasme, together with eleven known compounds. Their structures and configurations were elucidated by spectroscopic methods including 2D-NMR techniques. Sikokianin A, chamaechromone, and quercetin showed in vitro antiviral activity against HBsAg secretion.
Antimitotic and antifungal C-3/C-3''-biflavanones from Stellera chamaejasme.[Pubmed:15997133]
Chem Pharm Bull (Tokyo). 2005 Jul;53(7):776-9.
Two new C-3/C-3'' biflavanones, chamaejasmenin D (1) and isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), Sikokianin A (6), and chamaejasmenin C (7). Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively.
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