Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 40

  1. Cat.No. Product Name Information/Activity
  2. BCC7449 JP 1302 dihydrochloride JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Kb value (antagonist activity) of 16 nM and a Ki (binding affinity) value of 28 nM. JP 1302 dihydrochloride chemical structure
  3. BCC4923 Mirtazapine Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors. Mirtazapine chemical structure
  4. BCC6834 Rauwolscine hydrochloride Rauwolscine hydrochloride is a potent and specific α2 adrenergic receptor antagonist with a Ki of 12 nM. Rauwolscine hydrochloride chemical structure
  5. BCC6876 RS 79948 hydrochloride 186002-54-0 RS 79948 hydrochloride chemical structure
  6. BCC7021 RX 821002 hydrochloride 109544-45-8 RX 821002 hydrochloride chemical structure
  7. BCC6208 S 32212 hydrochloride 847871-78-7 S 32212 hydrochloride chemical structure
  8. BCC7795 SKF 86466 hydrochloride 86129-54-6 SKF 86466 hydrochloride chemical structure
  9. BCC6728 Spiroxatrine 1054-88-2 Spiroxatrine chemical structure
  10. BCN6268 Yohimbine Hydrochloride Yohimbine Hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine. Yohimbine Hydrochloride chemical structure
  11. BCC6813 Agmatine sulfate Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine sulfate chemical structure

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