Hypertension Research
Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.
Hypertension Research Products Targets
- Adenosine A2B Receptor (7)
- Adenosine A2A Receptor (11)
- Lipoxygenase (8)
- Leukotriene and Related Receptor (13)
- Bradykinin Receptor (12)
- Others (10)
- Cyclooxygenase (24)
- Apelin Receptor (5)
- 5-HT1F Receptor (2)
- 5-HT1E Receptor (1)
- 5-HT1D Receptor (13)
- 5-HT1B Receptor (20)
- 5-HT1A Receptor (25)
- 5-HT2C Receptor (23)
- 5-HT2B Receptor (12)
- 5-HT2A Receptor (25)
- Natriuretic Peptide Receptor (4)
- Mineralocorticoid Receptor (7)
- Angiotensin-Converting Enzyme (8)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- Histamine H4 Receptor (12)
- Histamine H3 Receptor (22)
- Histamine H2 Receptor (10)
- Histamine H1 Receptor (17)
- Adenosine A3 Receptor (8)
- Adenosine A1 Receptor (12)
- Calcitonin and Related Receptor (10)
- VIP Receptor (7)
- Vasopressin Receptor (6)
- NO donors and precursors (9)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- Urotensin-II Receptor (8)
- ETB Receptor (6)
- ETA Receptor (5)
- Angiotensin AT2 Receptor (3)
- Angiotensin AT1 Receptor (9)
- M5 Receptor (2)
- M4 Receptor (3)
- M3 Receptor (4)
- Purinergic (P2Y) Receptor (31)
- M2 Receptor (5)
- M1 Receptor (8)
- Neuromedin U (2)
- NKCC (2)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
- Protease-Activated Receptor (23)
- Prostanoid Receptor (24)
- Sphingosine-1-Phosphate Receptor (13)
- Phosphodiesterase (34)
Products for Hypertension Research - Page 35
- Cat.No. Product Name Information/Activity
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BCC7118
HEMADO
HEMADO is a potent and selective adenosine A3 receptor agonist with a Ki of 1.1 nM at the human A3 subtype.
-
BCC6106
MRE 3008F20
MRE3008F20 is a highly potent and selective antagonist of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM.
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BCC6972
MRS 1220
183721-15-5
-
BCC5753
MRS 1334
192053-05-7
-
BCC7238
PSB 10 hydrochloride
591771-91-4
-
BCC7239
PSB 11 hydrochloride
453591-58-7
-
BCC7030
VUF 5574
280570-45-8
-
BCC6912
A 61603 hydrobromide
107756-30-9
-
BCC6833
Cirazoline hydrochloride
Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM).
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BCC4333
Oxymetazoline HCl
2315-02-8


