Neuroscience Research

Neuroscience is the study of the nervous system - one of the major mammalian systems responsible for sustaining life. The central nervous system (CNS) and peripheral nervous system (PNS) work in concert to coordinate basic functions such as moving and breathing, as well as 'higher order' functions including thought, speech and emotion.

Neuroscience Research Products Areas

Products for Neuroscience Research - Page 107

Cat.No. Product Name Information/Activity
BCC3940 AY 9944 dihydrochloride AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol.
BCC3939 Ciliobrevin A Ciliobrevin A is a hedgehog (Hh) signaling pathway inhibitor with median inhibitory concentration (IC50) less than 10 μM.
BCN2964 Cyclopamine Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay.
BCC1587 GANT 58 GANT 58 is a potent Gli antagonist that inhibits GLI1-induced transcription with IC50 of 5 μM.
BCC1090 GANT61 GANT 61 is an inhibitor of Gli1 and Gli2 targeting the Hedgehog/GLI pathway.
BCC3938 HPI 1 Inhibits Hedgehog signaling
BCC3936 JK 184 JK184 is a potent Hedgehog (Hh) pathway inhibitor with IC50 of 30 nM in mammalian cells.
BCC7950 MRT 10 330829-30-6
BCC3941 SANT-1 SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling. SANT-1 shows IC50s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 assay, respectively.
BCC3937 SANT-2 329196-48-7