Neuroscience Research

Neuroscience is the study of the nervous system - one of the major mammalian systems responsible for sustaining life. The central nervous system (CNS) and peripheral nervous system (PNS) work in concert to coordinate basic functions such as moving and breathing, as well as 'higher order' functions including thought, speech and emotion.

Neuroscience Research Products Areas

Products for Neuroscience Research - Page 102

Cat.No. Product Name Information/Activity
BCC7874 KS 176 KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
BCC7334 MK 571 MRP1 inhibitor; also CysLT<sub>1</sub> (LTD<sub>4</sub>) inverse agonist
BCC4832 Probenecid Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels.
BCC2027 Valspodar Valspodar is a selective P-glycoprotein inhibitor that has been used as an experimental cancer treatment and chemosensitizer.
BCC7764 Reversan Reversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor.
BCC3878 LY335979 (Zosuquidar 3HCL) Zosuquidar trihydrochloride is an inhibitor of P-glycoprotein with a Ki value of 59 nM.
BCN2961 Ingenol 3-Angelate Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
BCC6203 A 484954 A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM.
BCC7370 Arcyriaflavin A Potent cdk4/cyclin D1 and CaM Kinase II inhibitor. Antiviral agent (anti-HCMV)
BCC7153 Autocamtide-2-related inhibitory peptide Selective CaM kinase II inhibitor