Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 16

  1. Cat.No. Product Name Information/Activity
  2. BCC1259 Flumazenil Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses. Flumazenil chemical structure
  3. BCC6107 Flunitrazepam 1622-62-4 Flunitrazepam chemical structure
  4. BCN6250 Hispidulin Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM. Hispidulin chemical structure
  5. BCC5970 Lorazepam 846-49-1 Lorazepam chemical structure
  6. BCC6745 PK 11195 PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively. PK 11195 chemical structure
  7. BCC7230 Ro 15-4513 Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR). Ro15-4513 is a potent ethanol antagonist. Ro15-4513 has anti-anxiety effect. Ro 15-4513 chemical structure
  8. BCC7228 Ro 19-4603 99632-94-7 Ro 19-4603 chemical structure
  9. BCC6087 TCS 1105 185391-33-7 TCS 1105 chemical structure
  10. BCC5197 Zaleplon 151319-34-5 Zaleplon chemical structure
  11. BCC7227 ZK 93423 hydrochloride Potent benzodiazepine agonist ZK 93423 hydrochloride chemical structure

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