Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 14

  1. Cat.No. Product Name Information/Activity
  2. BCC7387 (-)-Bicuculline methiodide 40709-69-1 (-)-Bicuculline methiodide chemical structure
  3. BCC6555 (-)-Bicuculline methobromide (-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABAA receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons. (-)-Bicuculline methobromide chemical structure
  4. BCN3763 (-)-Bicuculline methochloride (-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons. (-)-Bicuculline methochloride chemical structure
  5. BCN1238 (+)-Bicuculline (+)-Bicuculline is a light-sensitive competitive antagonist of GABA-A receptor. (+)-Bicuculline chemical structure
  6. BCC3782 Furosemide Furosemide is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema. Furosemide chemical structure
  7. BCC6193 PHP 501 trifluoroacetate 1236105-75-1 PHP 501 trifluoroacetate chemical structure
  8. BCC5705 Picrotoxin Picrotoxin (Cocculin) is a natural noncompetitive antagonist of GABAA receptor, binds to the interface pocket on the GABAR. Picrotoxin (Cocculin) causes overstimulation and induces convulsions. Picrotoxin chemical structure
  9. BCC7266 SCS 3232-36-8 SCS chemical structure
  10. BCC6997 SR 95531 hydrobromide Gabazine is a selective and competitive antagonist of GABAA receptor, with an IC50 of ~0.2 μM for GABA receptor. SR 95531 hydrobromide chemical structure
  11. BCC7510 TB 21007 207306-50-1 TB 21007 chemical structure

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