Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 13

  1. Cat.No. Product Name Information/Activity
  2. BCC6575 Isoguvacine hydrochloride Isoguvacine hydrochloride is a GABA receptor agonist. Isoguvacine hydrochloride chemical structure
  3. BCC7617 L-838,417 286456-42-6 L-838,417 chemical structure
  4. BCC6170 MK 0343 MK0343 (MRK-409) is an orally bioavailable GABAA receptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic. MK 0343 chemical structure
  5. BCC6070 MRK 016 783331-24-8 MRK 016 chemical structure
  6. BCC6593 Muscimol Potent GABA<sub>A</sub> agonist Muscimol chemical structure
  7. BCC6564 TACA 38090-53-8 TACA chemical structure
  8. BCC7819 TCS 1205 355022-97-8 TCS 1205 chemical structure
  9. BCC6803 THIP hydrochloride Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid analgesic and has hypnotic activities. THIP hydrochloride chemical structure
  10. BCC6169 TP 003 628690-75-5 TP 003 chemical structure
  11. BCC6563 ZAPA sulfate 371962-01-5 ZAPA sulfate chemical structure

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