Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 16

  1. Cat.No. Product Name Information/Activity
  2. BCC7807 WAY 208466 dihydrochloride 1207064-61-6 WAY 208466 dihydrochloride chemical structure
  3. BCC7650 BGC 20-761 High affinity 5-HT<sub>6</sub> antagonist BGC 20-761 chemical structure
  4. BCC6127 MS 245 oxalate 275363-58-1 MS 245 oxalate chemical structure
  5. BCC7629 NPS ALX Compound 4a dihydrochloride NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM, which also has a great binding affinity with Ki of 0.2 nM. NPS ALX Compound 4a dihydrochloride chemical structure
  6. BCC7512 Ro 04-6790 202466-68-0 Ro 04-6790 chemical structure
  7. BCC7216 SB 258585 hydrochloride 1216468-02-8 SB 258585 hydrochloride chemical structure
  8. BCC1924 SB 271046 hydrochloride SB271046 Hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9. SB 271046 hydrochloride chemical structure
  9. BCC7750 SGS 518 oxalate 445441-27-0 SGS 518 oxalate chemical structure
  10. BCC6709 Metergoline Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors. Metergoline chemical structure
  11. BCC5663 2-Methyl-5-hydroxytryptamine hydrochloride 2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects. 2-Methyl-5-hydroxytryptamine hydrochloride chemical structure

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