Sleep Research

Sleep is characterized by altered consciousness, it is split into two distinct stages- rapid eye movement (REM) and non-REM. The circadian clock controls the pattern of sleep and wakefulness. It is regulated by the light levels, temperature, metabolites, neurotransmitters, neuropeptides, and neurohormones, which cause a daily fluctuation in expression levels of many sleep-related genes.

Sleep Research Products Targets

Products for Sleep Research - Page 21

Cat.No. Product Name Information/Activity
BCC7819 TCS 1205 355022-97-8
BCC6803 THIP hydrochloride Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid analgesic and has hypnotic activities.
BCC6169 TP 003 628690-75-5
BCC6563 ZAPA sulfate 371962-01-5
BCC7387 (-)-Bicuculline methiodide 40709-69-1
BCC6555 (-)-Bicuculline methobromide (-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABAA receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons.
BCN3763 (-)-Bicuculline methochloride (-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons.
BCN1238 (+)-Bicuculline (+)-Bicuculline is a light-sensitive competitive antagonist of GABA-A receptor.
BCC3782 Furosemide Furosemide is a loop diuretic inhibitor of Na+/2Cl-/K+ (NKCC) cotransporter of which used in the treatment of congestive heart failure and edema.
BCC6193 PHP 501 trifluoroacetate 1236105-75-1