Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN1881 | Calystegine B4 |
| 1. Calystegine B4 inhibits almond beta-glucosidase and pig kidney trehalase in a competitive manner, with a Ki value of 7.3 microM and 1.2 microM, respectively. | |
| BCN1882 | Calystegine B1 |
| 1. Calystegine B1 is a noncompetitive inhibitor of rice alpha-glucosidase, with a Ki value of 0.9 +/- 0.1 microM. 2. Calystegine B1 and Calystegine C1 are potent competitive inhibitors of the bovine, human, and rat beta-glucosidase activities, with Ki values of 150, 10, and 1.9 microM. | |
| BCN1884 | Calystegine A3 |
| 1. Calystegines A3 and B2 can effectively stabilize β-glucocerebrosidase, and consequently increase intracellular β-glucocerebrosidase activities in N370S fibroblasts. 2. Calystegines A3, B2, and C1 are glycosidase inhibitors. | |
| BCN1901 | Cocaine |
| 1. Cocaine is a powerfully addictive stimulant drug made from the leaves of the coca plant native to South America, it produces short-term euphoria. 2. Cocaine constricts blood vessels, dilates pupils, and increases body temperature, heart rate, and blood pressure. 3. Cocaine has a small number of accepted medical uses such as numbing and decreasing bleeding during nasal surgery. 4. Cocaine sensitizes VTA cells to the excitatory effects of both CRF and orexin-A, thus providing a mechanism by which stress induces Cocaine seeking. 5. Cocaine can cause headaches and gastrointestinal complications such as abdominal pain and nausea. Because cocaine tends to decrease appetite, chronic users can become malnourished as well. | |
| BCN1902 | Pseudococaine |
| 1. Pseudococaine produces high-voltage slow waves (HVSWs) in the EEG associated with behavioral depression. 2. Pseudococaine is more potent than cocaine in producing convulsions in the same monkeys. | |
| BCN1904 | Convolvine |
| 1. Convolvine and its derivatives exhibit pronounced antihypoxic, immunomodulating, and anti-inflammatory activity. 2. Convolvine blocks the M-receptors of the heart and intestine but raises the sensitivity of the M-receptors of the salivary gland and of the CNS,convolvine has revealed characteristics of a sedative and nootropic agent. 3. Convolvine and its derivatives exhibit cytotoxic activity, the alkaloids N-benzylconvolvine and N-chloroacetylconvolvine at concentrations of 10 ug/mL exhibit the greatest activity against HeLa and Hep cancer cell cultures. | |
| BCN1905 | Convolamine |
| 1. Convolamine may have antihypoxic, immunomodulating, and anti-inflammatory activity. | |
| BCN1907 | Ecgonine |
| 1. Ecgonine is a promising marker of cocaine ingestion. | |
