Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2053 | Australine |
| 1. Australine is a potent and specific inhibitor of amyloglucosidase. 2. Australine inhibits the glycoprotein processing enzyme glucosidase I, and has slight activity toward glucosidase II. | |
| BCN2054 | Alexine |
| 1. Alexine is a weak inhibitor of glucosidase activity. | |
| BCN2055 | Uplandicine |
| 1. Uplandicine exhibits antibacterial effects with a MIC of 1.7 mg/ml in E. coli . | |
| BCN2056 | Adonifoline |
| 1. Adonifoline is a hepatotoxic pyrrolizidine alkaloid. | |
| BCN2057 | Anacrotine |
| 1. Anacrotine produces much more severe lung damage than most other pyrrolizidine alkaloids. | |
| BCN2060 | Axillaridine |
| 1. Axillaridine shows significant activity as antiestrogen binding site-inhibitory agents. 2. The complexation of AChE with Axillaridine-A, results in the reduction of gorge size due to interaction between the ligand and the active site residues. | |
| BCN2063 | Isoline |
| 1. Isoline decreases the cellular GSH and the ratio of GSH and oxidizes glutathione in a time- and concentration-dependent manner in L-02 cells. 2. Isoline can induce different oxidative injury in various important mouse organs, and of which liver is the most sensitive organ. 3. An in silico drug target searching program INVDOCK identified 2 potential protein targets of Isoline. 4. l-Buthionine-(S, R)-sulfoximine (BSO) and mercaptosuccinic acid (MA), inhibitors of GCL and GPx, both augmented Isoline-induced cytotoxicity in cultured mice hepatocytes. | |
| BCN2066 | Doronenine |
| 1. Doronenine shows moderate cytotoxicity on cancerous U-937 cells. | |
