Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 145 - 152 of 9359 hot products
| Catalog No. | Product Name |
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| BCC1324 | A-867744 |
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Positive allosteric modulator of <span class='symbol'>α</span>7 nAChRs (IC<sub>50</sub> values are 0.98 and 1.12 <span class='symbol'>μ</span>M for human and rat <span class='symbol'>α</span>7 receptor ACh-evoked currents respectively, in <em>X. laevis</em> oocytes). Displays no activity at 5-HT<sub>3A</sub>, <span class='symbol'>α</span>3<span class='symbol'>β</span>4 or <span class='symbol'>α</span>4<span class='symbol'>β</span>2 nAChRs. Brain penetrant.
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| BCC1327 | Acamprosate calcium |
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GABA receptor agonist and modulator of glutamatergic systems. Reduces alcohol consumption in animal models of alcohol addiction.
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| BCC1332 | AH 6809 |
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Antagonist at prostaglandin EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45).
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| BCC1334 | AKT inhibitor VIII |
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Potent and selective dual Akt1 and 2 inhibitor (IC50 values are 50 and 210 nM, respectively). Selective for Akt1 and 2 over a panel of other tyrosine and serine/threonine kinases. Sensitizes LnCaP cells to TRAIL (TNF-related apoptosis-inducing ligand) induced apoptosis. Active in vivo.
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| BCC1353 | AM630 |
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CB<sub>2</sub> antagonist/inverse agonist (K<sub>i</sub> = 31.2 nM) that displays 165-fold selectivity over CB<sub>1</sub> receptors. Behaves as a weak partial/inverse agonist at CB<sub>1</sub> receptors.
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| BCC1366 | AR-A014418 |
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Selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC<sub>50</sub> = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC<sub>50</sub> values are > 100 <span class='symbol'>μ</span>M) and over 26 other kinases. Inhibits <span class='symbol'>β</span>-amyloid-mediated neurodegeneration in hippocampal slices.
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| BCC1367 | AR-C155858 |
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Inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2 (Ki values are 2.3 and <10 nM respectively). Exhibits no activity at MCT4. Blocks proliferation of Raji lymphoma cells in vitro. Inhibits glycolysis and glutathione synthesis in cancer cells.
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| BCC1368 | ARRY-520 R enantiomer |
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ARRY-520 R enantiomer is the R-enantiomer of ARRY-520. ARRY-520 is a synthetic kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM.
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