Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 193 - 200 of 9359 hot products
| Catalog No. | Product Name |
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| BCC1576 | FK 3311 |
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Cyclooxygenase-2 (COX-2) inhibitor. Inhibits zymosan-induced prostaglandin E2 production by rat peritoneal neutrophils in vitro and adjuvant-induced arthritis in vivo. Anti-inflammatory.
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| BCC1578 | Flecainide acetate |
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Open Na+ channel blocker that inhibits fast Na+ current in cardiac muscle in a use- and concentration-dependent manner. Orally-active class Ic antiarrhythmic agent.
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| BCC1585 | gamma-secretase modulator 3 |
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gamma-secretase modulator 3 is a gamma-secretase modulator.
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| BCC1587 | GANT 58 |
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GLI antagonist that inhibits GLI1-induced transcription (IC<sub>50</sub> = 5 <span class='symbol'>μ</span>M). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity <em>in vivo</em>.
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| BCC1600 | GPR120 modulator 2 |
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GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120).
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| BCC1606 | GSK2606414 |
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Potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK over HR1 and PKR. Inhibits thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells. Attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Orally bioavailable.
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| BCC1609 | Guanfacine hydrochloride |
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Selective <span class='symbol'>α</span><sub>2A</sub>-adrenoceptor agonist (K<sub>d</sub> = 31 nM). Displays 60-fold selectivity over <span class='symbol'>α</span><sub>2B</sub>-adrenoceptors. Also available as part of the <span class='symbol'>α</span><sub>2</sub>-Adrenoceptor.
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| BCC1614 | GW843682X |
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Selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). Displays > 100-fold selectivity over ~30 other kinases tested including cdk1 and cdk2. Inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts.
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