Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN7306 Gentiside J
1. Gentiside J is a potent inducer of neurite outgrowth on PC12 cells.
BCN7307 1beta,10beta-Epoxydesacetoxymatricarin
1. 1beta,10beta-Epoxydesacetoxymatricarin shows high anti-hypercholesterolemic potential.
BCN7308 Paucinervin A
1. Paucinervin A has inhibitory effect against HeLa cell growth, with the IC50 value of 29.5 microM.
BCN7309 Pachysamine M
1. Pachysamine M shows inhibitory activities against multiple types of cancer cells.
BCN6453 Fumitremorgin B
1. Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes. 2. Fumitremorgin B exhibits antifungal activities, it also shows significant toxicity toward brine shrimps,with the median lethal concentration (LC(50)) value of 13.6 ug/mL. 3. Fumitremorgin B possess antifeedant activity against armyworm larvae. 4. Fumitremorgin B shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M phase, with the MIC value of 26.1 microM.
BCN7313 Isoaltenuene
1. Isoaltenuene shows antibiotic activity against Gram-positive bacteria. 2. Isoaltenuene exhibits cytotoxic activity against lung cancer cell line A549, breast cancer cell line MDA-MB-231 and pancreatic cancer cell line PANC-1. 3. Isoaltenuene shows a minor phytotoxic activity on tomato leaves at level of 20 ug/spot .
BCN7323 Boscialin
1. Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM.
BCN7330 ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide
1. ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide shows significant cytotoxic activity against ANA-1 and Jurkat cells with IC50 values 7.12 x 10(-3) and 1.79 x 10(-2) microM.